COMPARISON BETWEEN EFFICACY OF TAMSULOSIN AND TERAZOSININ ALPHA-ADRENERGIC BLOCKERS IN SPONTANEOUS PASSAGE OF URETER STONES AFTER ESWL (A DOUBLE BLIND CLINICAL TRIAL)

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PEDRAM P.; TAJARI H.R.; KESHTKAR ABAS ALI; GHAZI MOGHADAM B.; AMIDI A.

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2009 | Volume:52 | Issue:2 Page(s): 87-94

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Title

COMPARISON BETWEEN EFFICACY OF TAMSULOSIN AND TERAZOSININ ALPHA-ADRENERGIC BLOCKERS IN SPONTANEOUS PASSAGE OF URETER STONES AFTER ESWL (A DOUBLE BLIND CLINICAL TRIAL)

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Keywords

α ADRENERGIC RECEPTORS' ANTAGONISTQ2

ESWLQ3

NEPHROLITHIASISQ3

TAMSULOSINQ3

TERAZOSINQ3

Abstract

Introduction: NEPHROLITHIASIS has a high prevalence in population. Our objective was to compare time of stone passage, severity of pain, frequency of the use of analgesics and the course of disability between groups A, B and C.Materials and Methods: In this randomized controlled trial study, 240 patients were selected .inclusion criteria was all patient with 5-9mm stone diameter, and exclusion criteria was opium addiction. All of patients were categorized in 3 groups with Block Balance Randomize and double blind method. Each group consisted of 80 persons. In group A (i.e. control group) patients were given daily Diclofenac suppositories of 100mg and Diclofenac tablets of 25mg. In group B patients were given TAMSULOSIN tablets of 0.4 mg in addition to routine treatment and in group C patients were given TERAZOSIN tablets of 2 mg in addition to routine treatment.Results: The rate of ureteral stone passage in group B (85.5%) was more than group A (80%) and group C (83.3%), the mean expulsion time group A with 14.9 days was more than group B (12.1 days) and group C (12.2 days), also severity of pain on the basis of VAS chart in group B (4.7) less than group A (5.5) and C (5.2), extra analgesic requirement in α blockers group (B:4 patients and C:2 patients) less than control group (8 patients), and all of these were non significantly different Patients were visited three months after lithotripsy.Conclusion: a blockers are decrease symptoms of pain and no effective response on expulsion of stones.

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APA: Copy

PEDRAM, P., TAJARI, H.R., KESHTKAR, ABAS ALI, GHAZI MOGHADAM, B., & AMIDI, A.. (2009). COMPARISON BETWEEN EFFICACY OF TAMSULOSIN AND TERAZOSININ ALPHA-ADRENERGIC BLOCKERS IN SPONTANEOUS PASSAGE OF URETER STONES AFTER ESWL (A DOUBLE BLIND CLINICAL TRIAL). MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 52(2), 87-94. SID. https://sid.ir/paper/51976/en

Vancouver: Copy

PEDRAM P., TAJARI H.R., KESHTKAR ABAS ALI, GHAZI MOGHADAM B., AMIDI A.. COMPARISON BETWEEN EFFICACY OF TAMSULOSIN AND TERAZOSININ ALPHA-ADRENERGIC BLOCKERS IN SPONTANEOUS PASSAGE OF URETER STONES AFTER ESWL (A DOUBLE BLIND CLINICAL TRIAL). MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;52(2):87-94. Available from: https://sid.ir/paper/51976/en

IEEE: Copy

P. PEDRAM, H.R. TAJARI, ABAS ALI KESHTKAR, B. GHAZI MOGHADAM, and A. AMIDI, “COMPARISON BETWEEN EFFICACY OF TAMSULOSIN AND TERAZOSININ ALPHA-ADRENERGIC BLOCKERS IN SPONTANEOUS PASSAGE OF URETER STONES AFTER ESWL (A DOUBLE BLIND CLINICAL TRIAL),” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 52, no. 2, pp. 87–94, 2009, [Online]. Available: https://sid.ir/paper/51976/en

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