SKIN CANCER AFTER RENAL TRANSPLANTATION

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NAZEMIAN F.; NAGHIBI M.

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Journal Paper

Paper Information

Journal: MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES Year:2004 | Volume:47 | Issue:84 Page(s): 224-230

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Information Journal Paper

Title

SKIN CANCER AFTER RENAL TRANSPLANTATION

Author(s)

NAZEMIAN F. | NAGHIBI M. | Issue Writer Certificate

Keywords

SKIN CANCERQ4

RENAL TRANSPLANTATIONQ3

KAPOSI SARCOMA (KS)Q4

SCC (SQUOMUS CELL CARCINOMA)Q3

BCC (BASAL CELL CARCINOMA)Q4

Abstract

Introdaction: The incidence of SKIN CANCER in transplant recipient is higher than general population. Therefore, careful phyiscal examination to detect skin malignancies is essential in the long-term prognosis of these patients. This study was carried out to identify risk factors associated with variant of skin tumor from 1989 to 2002.Material and Method: 620 kidney transplants (223 women and 397 men) were performed in Imam Reza hospital. The patients were followed up for one to 14 years. They were treated with cyclosporine, prednisolone, Azathioprine or Mycophenolate Mofetiel.Results: Skin tumor was observed in 12 patients (10 men and 2 women). Diagnosis was based on biopsy.Kaposi sarcoma was occurred earlier than other tumor and accounted for 50% (6 out of 12) of post-transplantation skin tumor. Five patients had SCC and one ofthem had BCC. Kaposi sarcoma on the average appeared 14 months after transplantation. SCC appeared later than other type of cancers occurring after transplantation (90±36 months).All patients who had SCC and BCC were male and they were older than 40 years old, when they received kidney.SCC and BCC occurred on the head and neck in all patients who did have these tumors. All patients with kaposi sarcoma had skin involvement. 33.3 % of these patients had visceral lesions.In our study the incidence of malignancy was observed to be less than those reported in other reports (2% instead of 6 % -24 %) and kaposi sarcoma was the most frequent neoplasm.The result showed a significant relationship between recipient's age and sex with skin tumor. Skin tumor was observed to be more common in men and older patients.Conclusion: In addition to standard established treatment for each malignancy, reduction of immunosuppression was performed. Complete remission was observed in two patients who had kaposi sarcoma and three patients who had SCC while the other patients didn't respond to the treatment.

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APA: Copy

NAZEMIAN, F., & NAGHIBI, M.. (2004). SKIN CANCER AFTER RENAL TRANSPLANTATION. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 47(84), 224-230. SID. https://sid.ir/paper/51982/en

Vancouver: Copy

NAZEMIAN F., NAGHIBI M.. SKIN CANCER AFTER RENAL TRANSPLANTATION. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2004;47(84):224-230. Available from: https://sid.ir/paper/51982/en

IEEE: Copy

F. NAZEMIAN, and M. NAGHIBI, “SKIN CANCER AFTER RENAL TRANSPLANTATION,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 47, no. 84, pp. 224–230, 2004, [Online]. Available: https://sid.ir/paper/51982/en

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