THE PRE-EMPTIVE ANALGESIC EFFECT OF PERITONSILLAR INFILTRATION OF KETAMINE FOR POSTOPERATIVE PAIN RELIEF IN CHILDREN FOLLOWING TONSILLECTOMY

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SAFAVI MOHAMMAD REZA; HONARMAND AZIM; BARATI B.; MAHJOUBIPOUR H.

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2009 | Volume:52 | Issue:1 Page(s): 37-42

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Title

THE PRE-EMPTIVE ANALGESIC EFFECT OF PERITONSILLAR INFILTRATION OF KETAMINE FOR POSTOPERATIVE PAIN RELIEF IN CHILDREN FOLLOWING TONSILLECTOMY

Author(s)

SAFAVI MOHAMMAD REZA | HONARMAND AZIM | BARATI B. | MAHJOUBIPOUR H. | Issue Writer Certificate

Keywords

KETAMINEQ2

PAINQ3

POSTOPERATIVEQ2

TONSILLECTOMYQ3

Abstract

Introduction: In several studies, theuse of KETAMINE for the preemptive analgesiain the management of POSTOPERATIVE PAIN is controversial. The purpose of our study was the clinical assessment of the efficacy of preincisional peritonsillar infiltration of two doses of KETAMINEon POSTOPERATIVE PAIN relief compared with preincisional peritonsillar infiltration of saline in children undergoing TONSILLECTOMY.Materials and Methods: A total of Seventy-five ASA (American Society Anesthesia) physical status I and II patients, aged 3 to 12 years, scheduled for TONSILLECTOMY were enrolled in this randomized, double-blinded, placebo-controlled study. Patients were divided into three groups of 25 each and received a local peritonsillar infiltration of 0.9% saline (Group A), KETAMINE 0.5 mg/kg (Group B), or KETAMINE 1 mg/kg (Group C). All medications were 2 ml in volume which applied 1 ml per tonsil 3 min prior to TONSILLECTOMY. The Children's Hospital Eastern Ontario PAIN Scale (CHEOPS) and Wilson sedation scale were used to evaluate PAIN levels and sedative condition, respectively.Results: Group A had significantly higher CHEOPS scores than group B and group C. Group B and group C had comparable scores, which were not statistically significant (p>0.05). During 24 hours after surgery, sixteen patients in group A and no patients in groups B or C needed analgesics (p<0.001).Conclusion: 0.5 or 1 mg/kg dose of KETAMINE, given at approximately 3 min before surgery by peritonsillar infiltration, provides efficient PAIN relief without side-effects in children undergoing TONSILLECTOMY.

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APA: Copy

SAFAVI, MOHAMMAD REZA, HONARMAND, AZIM, BARATI, B., & MAHJOUBIPOUR, H.. (2009). THE PRE-EMPTIVE ANALGESIC EFFECT OF PERITONSILLAR INFILTRATION OF KETAMINE FOR POSTOPERATIVE PAIN RELIEF IN CHILDREN FOLLOWING TONSILLECTOMY. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 52(1), 37-42. SID. https://sid.ir/paper/52252/en

Vancouver: Copy

SAFAVI MOHAMMAD REZA, HONARMAND AZIM, BARATI B., MAHJOUBIPOUR H.. THE PRE-EMPTIVE ANALGESIC EFFECT OF PERITONSILLAR INFILTRATION OF KETAMINE FOR POSTOPERATIVE PAIN RELIEF IN CHILDREN FOLLOWING TONSILLECTOMY. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;52(1):37-42. Available from: https://sid.ir/paper/52252/en

IEEE: Copy

MOHAMMAD REZA SAFAVI, AZIM HONARMAND, B. BARATI, and H. MAHJOUBIPOUR, “THE PRE-EMPTIVE ANALGESIC EFFECT OF PERITONSILLAR INFILTRATION OF KETAMINE FOR POSTOPERATIVE PAIN RELIEF IN CHILDREN FOLLOWING TONSILLECTOMY,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 52, no. 1, pp. 37–42, 2009, [Online]. Available: https://sid.ir/paper/52252/en

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