EVALUATION OF ANTIMICROBIAL RESISTANCE IN COMMUNITY AND NOSOCOMIAL ST. AUREUS

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SARVGHAD S.M.R.; NADERI H.; RASHED T.; FARAMARZI H.; SHAKERI M.T.

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Journal Paper

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Journal: MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES Year:2005 | Volume:48 | Issue:88 Page(s): 141-148

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Title

EVALUATION OF ANTIMICROBIAL RESISTANCE IN COMMUNITY AND NOSOCOMIAL ST. AUREUS

Author(s)

Keywords

STAPHYLOCOCCUS AUREUSQ3

METHICILLINQ3

MRSAQ2

MICROBIAL RESISTANTQ2

E-TESTQ4

DISK DIFFUSIONQ4

Abstract

Introduction: STAPHYLOCOCCUS AUREUS is a common pathogen in community-acquired and nosocomial infections, and inappropriate use of antibiotics during recent decades resulted in spreading MRSA isolates. According to some studies 60% of its hospital acquired staphylococcal infections were reported to be resistant to meticillin. The aim of present study was to determine the prevalence of MRSA among clinical isolates in Imam Reza General Hospital of Mashhad. Material and Methods: In present article we performed E-TEST and DISK DIFFUSION methods to determine the prevalence of MRSA among 115 isolates obtained from different units in Imam Reza general hospital of Mashad. Results: The results show that 69 isolates (60%) were nosocomial and 46 (40%) was community acquired. MRSA was the ethiologic agents in 75.4% of nosocomial infections, while most of community acquired infections (93.3%) were sensitive to METHICILLIN. Almost all of the isolates obtained from bum unit (30 isolates) were MRSA. All of the isolates were vancomycin sensitive but penicillin resistant by DISK DIFFUSION method. From 33 isolates which were resistant to METHICILLIN by E-TEST, 9 (27.3%) reported sensitive by Oxacillin disk; hence its usefulness for practical means remains doubtful.Conclusion: If our results would be confirmed by future studies, it seems that MRSA has a very high prevalence in Iran, whose control and eradication demands a very solid and subtle program.

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References

DETERMINATION OF PREVALENCE OF METHICILLIN RESISTANT STAPHYLOCOCCUS INFECTIONS THROUGH MEASUREMENT OF MICS OF S. AUREUS ISOLATES IMAM HOSPITAL (NOVEMBER 2001 TO JANUARY 2003)

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APA: Copy

SARVGHAD, S.M.R., NADERI, H., RASHED, T., FARAMARZI, H., & SHAKERI, M.T.. (2005). EVALUATION OF ANTIMICROBIAL RESISTANCE IN COMMUNITY AND NOSOCOMIAL ST. AUREUS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 48(88), 141-148. SID. https://sid.ir/paper/52264/en

Vancouver: Copy

SARVGHAD S.M.R., NADERI H., RASHED T., FARAMARZI H., SHAKERI M.T.. EVALUATION OF ANTIMICROBIAL RESISTANCE IN COMMUNITY AND NOSOCOMIAL ST. AUREUS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;48(88):141-148. Available from: https://sid.ir/paper/52264/en

IEEE: Copy

S.M.R. SARVGHAD, H. NADERI, T. RASHED, H. FARAMARZI, and M.T. SHAKERI, “EVALUATION OF ANTIMICROBIAL RESISTANCE IN COMMUNITY AND NOSOCOMIAL ST. AUREUS,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 48, no. 88, pp. 141–148, 2005, [Online]. Available: https://sid.ir/paper/52264/en

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