EFFECT OF SINGLE DOSE FETAL BRAIN EXTRACT ON SPINAL CORD MOTONEURON SURVIVAL FOLLOWING SCIATIC NERVE TRANSECTION IN THE RAT

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NIKRAVESH M.R.; BEHNAM RASOULI MORTEZA; MAHDAVI SHAHRI N.; TEHRANIPOUR M.

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Journal: Iranian Journal of Basic Medical Sciences Year:2003 | Volume:6 | Issue:1 (17) Page(s): 70-74

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Title

EFFECT OF SINGLE DOSE FETAL BRAIN EXTRACT ON SPINAL CORD MOTONEURON SURVIVAL FOLLOWING SCIATIC NERVE TRANSECTION IN THE RAT

Author(s)

NIKRAVESH M.R. | BEHNAM RASOULI MORTEZA | MAHDAVI SHAHRI N. | TEHRANIPOUR M. | Issue Writer Certificate

Keywords

FETAL BRAIN EXTRACTQ4

MOTONEURONSQ4

SCIATIC NERVEQ3

RATQ2

Abstract

The SCIATIC NERVE of 24 adult male wistar RATs were exposed and transected in the mid thigh (gluteal muscles region). RATs were divided in 2 experimental and control groups. The effect of single dose of FETAL BRAIN EXTRACT (FBE) treatment on motoneuron survival was investigated experimentally and compared with untreated (control group). This study showedthat by 6 weeks post-injury, nearly 80% of MOTONEURONS survived in experimental models (treated by FBE), while only about 40% of MOTONEURONS survived in control animals (nerve transected only). This data indicates that treatment with a single dose of FBE at time of ingury can promote the lesioned MOTONEURONS in anterior horn of spinal cord of experimental significant in comparison with control group.

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APA: Copy

NIKRAVESH, M.R., BEHNAM RASOULI, MORTEZA, MAHDAVI SHAHRI, N., & TEHRANIPOUR, M.. (2003). EFFECT OF SINGLE DOSE FETAL BRAIN EXTRACT ON SPINAL CORD MOTONEURON SURVIVAL FOLLOWING SCIATIC NERVE TRANSECTION IN THE RAT. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 6(1 (17)), 70-74. SID. https://sid.ir/paper/52398/en

Vancouver: Copy

NIKRAVESH M.R., BEHNAM RASOULI MORTEZA, MAHDAVI SHAHRI N., TEHRANIPOUR M.. EFFECT OF SINGLE DOSE FETAL BRAIN EXTRACT ON SPINAL CORD MOTONEURON SURVIVAL FOLLOWING SCIATIC NERVE TRANSECTION IN THE RAT. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2003;6(1 (17)):70-74. Available from: https://sid.ir/paper/52398/en

IEEE: Copy

M.R. NIKRAVESH, MORTEZA BEHNAM RASOULI, N. MAHDAVI SHAHRI, and M. TEHRANIPOUR, “EFFECT OF SINGLE DOSE FETAL BRAIN EXTRACT ON SPINAL CORD MOTONEURON SURVIVAL FOLLOWING SCIATIC NERVE TRANSECTION IN THE RAT,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 6, no. 1 (17), pp. 70–74, 2003, [Online]. Available: https://sid.ir/paper/52398/en

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