INVESTIGATION OF MAST CELLS ASSOCIATION WITH MUSCLE FIBROSIS IN PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SABBAGH S.; RASHIDI I.; MOBARAKEH M.T.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Basic Medical Sciences Year:2004 | Volume:7 | Issue:3 (23) Page(s): 163-168

Download Full-Text

Persian Verion

View:

2,099

Download:

Cites:

Information Journal Paper

Title

INVESTIGATION OF MAST CELLS ASSOCIATION WITH MUSCLE FIBROSIS IN PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY

Author(s)

SABBAGH S. | RASHIDI I. | MOBARAKEH M.T. | Issue Writer Certificate

Keywords

DUCHENNE MUSCULAR DYSTROPHYQ3

MAST CELLSQ2

FIBROSISQ2

Abstract

DUCHENNE MUSCULAR DYSTROPHY (DMD) is the most common and severe type of muscular dystrophy which occurs due to the absence of the cytoskeletal protein of dystrophin. The gene that is responsible for DMD was localized in the XP21 of human genum. Severe weakness of the skeletal muscles seen in the DMD patients seemed to be due to the FIBROSIS, but the reasons for it were not revealed. It was shown that in lung FIBROSIS and scleroderma, MAST CELLS intervene with FIBROSIS. Thus, we decided to evaluate the relationship between FIBROSIS and number of the MAST CELLS in DMD patients.This research was done on 51 DMD patients and due to clinical findings, we classified them into two groups: mild and severe. Having done different staining on sections of paraffin blocks of the patients muscle biopsies, we evaluated the degree of FIBROSIS and the number of MAST CELLS.Following by T-Test statistical method, the relationship between degree of FIBROSIS and number of MAST CELLS was found. Therefore, it could be concluded that MAST CELLS are responsible for mild and moderate FIBROSIS.

Cites

No record.

References

No record.

Cite

APA: Copy

SABBAGH, S., RASHIDI, I., & MOBARAKEH, M.T.. (2004). INVESTIGATION OF MAST CELLS ASSOCIATION WITH MUSCLE FIBROSIS IN PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 7(3 (23)), 163-168. SID. https://sid.ir/paper/52454/en

Vancouver: Copy

SABBAGH S., RASHIDI I., MOBARAKEH M.T.. INVESTIGATION OF MAST CELLS ASSOCIATION WITH MUSCLE FIBROSIS IN PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2004;7(3 (23)):163-168. Available from: https://sid.ir/paper/52454/en

IEEE: Copy

S. SABBAGH, I. RASHIDI, and M.T. MOBARAKEH, “INVESTIGATION OF MAST CELLS ASSOCIATION WITH MUSCLE FIBROSIS IN PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 7, no. 3 (23), pp. 163–168, 2004, [Online]. Available: https://sid.ir/paper/52454/en

Related Journal Papers