ANTIFUNGAL EFFECT OF AQUEOUS AND ETHANOLIC EXTRACT OF PINECONE (PINUSELDERICA) OF TEHRANON ON ASPERGILLUS NIGER AND CANDIDA ALBICANS

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KASHANI HANIE; TABATABAEI YAZDI FARIDEH; MORTAZAVI ALI; SHAHIDI FAKHRI

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Journal: Iranian Journal of Infectious Diseases and Tropical Medicine Year:2015 | Volume:20 | Issue:69 Page(s): 9-15

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Title

ANTIFUNGAL EFFECT OF AQUEOUS AND ETHANOLIC EXTRACT OF PINECONE (PINUSELDERICA) OF TEHRANON ON ASPERGILLUS NIGER AND CANDIDA ALBICANS

Author(s)

KASHANI HANIE | TABATABAEI YAZDI FARIDEH | MORTAZAVI ALI | SHAHIDI FAKHRI | Issue Writer Certificate

Keywords

PINE CONE OF TEHRANQ2

ANTIFUNGAL EFFECTQ2

CANDIDA ALBICANSQ3

ASPERGILLUSNIGERQ3

Abstract

Background and objective: In recent decades, infections of fungi caused significant increase in the rate of disease creation. Also, there are some limitations in the treatment of fungal diseases such as shortages and high price antifungal drugs, lateral complications and drug resistance caused Attention of researchers to new antifungal drugs, especially herbal medicines. The purpose of this study is studying on ANTIFUNGAL EFFECT of aqueous and ethanolic extract of pinecone (Pinuselderica) of Tehran on Aspergillus niger and CANDIDA ALBICANS. Then, the minimum inhibitory concentration and minimum bactericidal concentration was determined.Materials and methods: In this study, antifungal activity of aqueous and ethanolic extracts of pine tree of Tehran was investigated by two methods: agar disk diffusion methods at 4 levels (5, 30, 55 and 80 mg/ml) and pure plate method. Data were analyzed by SPSS 16software and the means were compared using by analysis of variance (ANOVA) at a significant level of P<0.05.Results: MIC and MFC of ethanolic extract for Aspergillus niger was 32mg/ml and 128mg/ml, respectively. On the other hand, MIC of ethanolic and aqueous extracts of C. albicans wasrespectively 32 and 8 mg/ml and MFC for thismold was 128 and 64mg/ml, respectively. In the agar diffusion method, all concentrations of methanol extract have inhibited effect on mentioned microorganismes. Aspergillus niger in mixed cultures showed dgreatest resistance when used to aqueous and ethanolic extract of PINE CONE OF TEHRAN.Conclusion: The results show that aqueous and especially ethanolic extracts of pinecone of Tehran have ananti fungal effects especially on candida. So there is hope that in the future by replacing this extraction stead of chemical anti fungal drugs that have many lateral complications. Therefore, these method beableto controlfungal infections.

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APA: Copy

KASHANI, HANIE, TABATABAEI YAZDI, FARIDEH, MORTAZAVI, ALI, & SHAHIDI, FAKHRI. (2015). ANTIFUNGAL EFFECT OF AQUEOUS AND ETHANOLIC EXTRACT OF PINECONE (PINUSELDERICA) OF TEHRANON ON ASPERGILLUS NIGER AND CANDIDA ALBICANS. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, 20(69), 9-15. SID. https://sid.ir/paper/52816/en

Vancouver: Copy

KASHANI HANIE, TABATABAEI YAZDI FARIDEH, MORTAZAVI ALI, SHAHIDI FAKHRI. ANTIFUNGAL EFFECT OF AQUEOUS AND ETHANOLIC EXTRACT OF PINECONE (PINUSELDERICA) OF TEHRANON ON ASPERGILLUS NIGER AND CANDIDA ALBICANS. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE[Internet]. 2015;20(69):9-15. Available from: https://sid.ir/paper/52816/en

IEEE: Copy

HANIE KASHANI, FARIDEH TABATABAEI YAZDI, ALI MORTAZAVI, and FAKHRI SHAHIDI, “ANTIFUNGAL EFFECT OF AQUEOUS AND ETHANOLIC EXTRACT OF PINECONE (PINUSELDERICA) OF TEHRANON ON ASPERGILLUS NIGER AND CANDIDA ALBICANS,” IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, vol. 20, no. 69, pp. 9–15, 2015, [Online]. Available: https://sid.ir/paper/52816/en

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