FREQUENCY OF HEPATITIS E ANTIBODY AMONG BLOOD DONORS IN HAMADAN

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REZAZADEH M.; HAJILOUEI M.; GACHKAR L.; YADEGARI D.; MANI KASHANI KH.; NAGHDI M.

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Journal: Iranian Journal of Infectious Diseases and Tropical Medicine Year:2006 | Volume:11 | Issue:34 Page(s): 13-18

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Title

FREQUENCY OF HEPATITIS E ANTIBODY AMONG BLOOD DONORS IN HAMADAN

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Keywords

HEPATITIS EQ3

HEPATITIS E VIRUS (HEV)Q2

BLOOD DONORSQ3

Abstract

Background and Objective: HEPATITIS E virus is the most common cause of acute adult hepatitis in Asia after hepatitis B, and it is the second cause of it, in North Africa and in the Middle East. HEPATITIS E virus infection spreads by the fecal-oral route and the transmission with contaminated water is more than with contaminated food. However, vertical, parentral (especially in endemic region) and sexually transmission are probable. Recently, transmission by blood transfusion has been diagnosed. Therefore, this study was done with the objective of determining the frequency of HEPATITIS E antibody among BLOOD DONORS, in Hamadan blood transfusion center.Materials and methods: This was a cross-sectional descriptive study, which was done on 280 BLOOD DONORS, in Hamadan blood transfusion center. Blood donated were evaluated for hepatitis B, hepatitis C, HIV, and syphilis in blood transfusion center. 3cc of blood were sent to laboratory at the temperature of -4˚c and were evaluated for the presence of HEPATITIS E antibody by ELISA method (by diapro kit, manufactured by Italy). Data such as age, sex, occupation, education, ocation, water states, positive familial or personal history of icter, addiction, surgery, hospitalization, blood transfusion and vaccination history against hepatitis B, were collected via questionnaires.Results: From 280 donors, 249 patients (88.9%) were men and 31 patients (11.1%) were women. HEPATITIS E antibody (Anti HEV-IgG) was detected in 36 persons (12.9%), and 7 persons (2.5%) had acute HEPATITIS E(Anti- HEV IgM). 205 persons were under 40 years. 31 of them (15.1%) were positive for anti- HEV IgG and 75 persons had 40 years old or more that 5 persons of them(6.7%) were positive for anti-HEY IgG which this differences was statistically significant (P<0.05). Male to female ratio for anti-HEY IgG presence was 0.6. The differences of education levels, occupation, the source of water, familial history of icter, history of hospitalization and blood transfusion, were not significant in positive and negative anti-HEY IgG (P>0.05). Whereas, the frequency of anti- HEV IgG positive persons in rural societies was more than urban societies (P<0.05). Conclusion: Regarding to, the serologic prevalence rate of HEPATITIS E among BLOOD DONORS in Hamadan as 12.9% and, the results of other studies done in Tabriz and Nahavand, Iran is probably endemic for this infection.

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APA: Copy

REZAZADEH, M., HAJILOUEI, M., GACHKAR, L., YADEGARI, D., MANI KASHANI, KH., & NAGHDI, M.. (2006). FREQUENCY OF HEPATITIS E ANTIBODY AMONG BLOOD DONORS IN HAMADAN. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, 11(34), 13-18. SID. https://sid.ir/paper/52873/en

Vancouver: Copy

REZAZADEH M., HAJILOUEI M., GACHKAR L., YADEGARI D., MANI KASHANI KH., NAGHDI M.. FREQUENCY OF HEPATITIS E ANTIBODY AMONG BLOOD DONORS IN HAMADAN. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE[Internet]. 2006;11(34):13-18. Available from: https://sid.ir/paper/52873/en

IEEE: Copy

M. REZAZADEH, M. HAJILOUEI, L. GACHKAR, D. YADEGARI, KH. MANI KASHANI, and M. NAGHDI, “FREQUENCY OF HEPATITIS E ANTIBODY AMONG BLOOD DONORS IN HAMADAN,” IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, vol. 11, no. 34, pp. 13–18, 2006, [Online]. Available: https://sid.ir/paper/52873/en

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