ANTIMICROBIAL RESISTANCE PATTERNS AMONG GRAM NEGATIVE BACILLI ISOLATED FROM PATIENTS WITH NOSOCOMIAL INFECTIONS BY E-TEST METHODS IN INTENSIVE CARE UNITS

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HADADI AZAR; RASOULINEZHAD MEHRNAZ; MALEKI ZOHREH; AHMADI ALI; ZIABASHAR HAGH N.

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Journal: Iranian Journal of Infectious Diseases and Tropical Medicine Year:2007 | Volume:11 | Issue:35 Page(s): 47-53

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Title

ANTIMICROBIAL RESISTANCE PATTERNS AMONG GRAM NEGATIVE BACILLI ISOLATED FROM PATIENTS WITH NOSOCOMIAL INFECTIONS BY E-TEST METHODS IN INTENSIVE CARE UNITS

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Keywords

NOSOCOMIALQ3

INFECTIONQ3

ANTIBIOTICSQ3

HOSPITALQ3

Abstract

Background and objectives: The objective was to investigate frequency of common NOSOCOMIAL INFECTIONs and the antimicrobial resistance among some of NOSOCOMIAL gram negative bacilli isolated from patients admitted in Intencive Care Units in Sina and Imam HOSPITAL in Tehrani Iran.Material and methods: From June 2004 to Decemeber 2005, 286 isolates of common gram negative bacilli (Klebsiella, Pseudomonas, Acinetobacter and E. coli) from 186 patients with NOSOCOMIAL INFECTIONs in Sina and Imam HOSPITALs were evaluated for the activity of imipenem, cefepime, ciprofloxacine, ceftriaxone and ceftazidime by E-Test methods. Results: The most common INFECTIONs were: primary septicemia (34.6%), pneumonia (27.6%), and urinary tract INFECTION (15.7%). The most fequent pathigens were Klebsiella spp (42 %), followed by pseudomonas (26%), Acinetobacted Spp. (19%), E Coli (13%). The most active antibiotic was Imipenem (85%). Studied microorganisms were 23% sensitive to Cefepime, 23% to Ciprofloxacin, 18% to Ceftazidime and 10% to Ceftrixone. The suseptibility rates of Klebsiella to Imipenem, Cefepime, Ciprofloxacin, Ceftazidime and Ceftrixone were 93, 21, 20, 10 and 5 percent; respectively. Likewise, these rates were 89, 22, 17, 25 and 25 percent for E. coli. Among Acinetobacter spp. susceptibility rate was 78% for imipenem and 18% for ceftazidime and cefepime and 22% for ciprofloxacin. Among Pseudomonas spp. the rate was 73% for imipenem and 32% for ciprofloxacin and 31% for cefepime and 27% for ceftazidime. Resistance to 3 drugs was 66%. Conclusion: The ANTIBIOTICS resistance among gram negative bacilli has increased, so antibiotic policy is urgently needed in order to delay the resistanse development.

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APA: Copy

HADADI, AZAR, RASOULINEZHAD, MEHRNAZ, MALEKI, ZOHREH, AHMADI, ALI, & ZIABASHAR HAGH, N.. (2007). ANTIMICROBIAL RESISTANCE PATTERNS AMONG GRAM NEGATIVE BACILLI ISOLATED FROM PATIENTS WITH NOSOCOMIAL INFECTIONS BY E-TEST METHODS IN INTENSIVE CARE UNITS. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, 11(35), 47-53. SID. https://sid.ir/paper/52930/en

Vancouver: Copy

HADADI AZAR, RASOULINEZHAD MEHRNAZ, MALEKI ZOHREH, AHMADI ALI, ZIABASHAR HAGH N.. ANTIMICROBIAL RESISTANCE PATTERNS AMONG GRAM NEGATIVE BACILLI ISOLATED FROM PATIENTS WITH NOSOCOMIAL INFECTIONS BY E-TEST METHODS IN INTENSIVE CARE UNITS. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE[Internet]. 2007;11(35):47-53. Available from: https://sid.ir/paper/52930/en

IEEE: Copy

AZAR HADADI, MEHRNAZ RASOULINEZHAD, ZOHREH MALEKI, ALI AHMADI, and N. ZIABASHAR HAGH, “ANTIMICROBIAL RESISTANCE PATTERNS AMONG GRAM NEGATIVE BACILLI ISOLATED FROM PATIENTS WITH NOSOCOMIAL INFECTIONS BY E-TEST METHODS IN INTENSIVE CARE UNITS,” IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, vol. 11, no. 35, pp. 47–53, 2007, [Online]. Available: https://sid.ir/paper/52930/en

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