EVALUATION OF RESPONSES TO PRP IN PDR PATIENTS AND ROLE OF SOME SYSTEMIC FACTORS ON IT

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RIAZI ESFAHANI M.; NILI AHMADABADI M.; KARKHANEH R.; IRANI Z.; LASHEYEI A.R.; MANSOURI M.R.; FAGHIHI H.; FOTOUHI A.

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Journal: JOURNAL OF CURRENT OPHTHALMOLOGY Year:2005 | Volume:18 | Issue:2 Page(s): 1-6

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Title

EVALUATION OF RESPONSES TO PRP IN PDR PATIENTS AND ROLE OF SOME SYSTEMIC FACTORS ON IT

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Keywords

PROLIFERATIVE DIABETIC RETINOPATHYQ4

PANRETINAL PHOTOCOAGULATIONQ4

HEMOGLOBIN A1CQ4

HYPERLIPIDEMIAQ4

PROTEINURIAQ4

Abstract

Purpose: To evaluate the response of patients with high risk characteristic PDR (PROLIFERATIVE DIABETIC RETINOPATHY) to PANRETINAL PHOTOCOAGULATION and the effects of systemic factors on it.Materials & Methods: The study was performed as a case-control study on 73 patients (100 eyes) with high risk PDR refering to Farabi Eye hospital between 1998 to 2000. Laboratory exams such as Hgb A1C, serum lipid profile, creatinin and PROTEINURIA were assessed before performing PRP (panretinal photocoagulation). Meanwhile body mass index and history of cardiovascular diseases were evaluated in all patients. The main outcome was the rate of response of PDR to PRP after four weeks and also at the end of follow up. Systemic factors have been compared between good response group with poor response eyes analyzed statistically.Results: One hundred eyes (belonging to 73 patients) were followed for 7.7 months (with the range of 4.5 to 11 months). There was a complete response in 55% and relative response in 24% of eyes after 4 weeks. 75% of cases who had a good response after 4 weeks, kept the same situation throughout the study. In type II diabetics the rate of good response to PRP was significantly higher than type I or mixed type diabetics (P<0.05). Good response to PRP was seen in 89.4% of women and 72.5% of men which was significantly different (P<0.05). Also there was less number of cases with good response in groups with ages younger than 20 years. We couldn't find a significant difference in the number of cases with good response to PRP with respect to other above mentioned factors.Conclusion: Although the severity of PDR seems to be the most important factor in determining the response to PRP but some other factors such as the type of diabetes, age, sex and good diabetic control should be considered in HRC PDR patients. Studies with more cases should be performed to evaluate the effects of other factors such as PROTEINURIA or HYPERLIPIDEMIA in these patients.

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APA: Copy

RIAZI ESFAHANI, M., NILI AHMADABADI, M., KARKHANEH, R., IRANI, Z., LASHEYEI, A.R., MANSOURI, M.R., FAGHIHI, H., & FOTOUHI, A.. (2005). EVALUATION OF RESPONSES TO PRP IN PDR PATIENTS AND ROLE OF SOME SYSTEMIC FACTORS ON IT. JOURNAL OF CURRENT OPHTHALMOLOGY, 18(2), 1-6. SID. https://sid.ir/paper/53049/en

Vancouver: Copy

RIAZI ESFAHANI M., NILI AHMADABADI M., KARKHANEH R., IRANI Z., LASHEYEI A.R., MANSOURI M.R., FAGHIHI H., FOTOUHI A.. EVALUATION OF RESPONSES TO PRP IN PDR PATIENTS AND ROLE OF SOME SYSTEMIC FACTORS ON IT. JOURNAL OF CURRENT OPHTHALMOLOGY[Internet]. 2005;18(2):1-6. Available from: https://sid.ir/paper/53049/en

IEEE: Copy

M. RIAZI ESFAHANI, M. NILI AHMADABADI, R. KARKHANEH, Z. IRANI, A.R. LASHEYEI, M.R. MANSOURI, H. FAGHIHI, and A. FOTOUHI, “EVALUATION OF RESPONSES TO PRP IN PDR PATIENTS AND ROLE OF SOME SYSTEMIC FACTORS ON IT,” JOURNAL OF CURRENT OPHTHALMOLOGY, vol. 18, no. 2, pp. 1–6, 2005, [Online]. Available: https://sid.ir/paper/53049/en

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