COMPARING THE EFFECTS OF MINIDOSAGE OF MARCAIN-PHENTANYL AND ROUTINE INTRATHECAL DOSAGE OF MARCAIN ON HEMODYNAMIC CHANGES DURING TURP SURGERY

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BAGHERZADI K.; KOUZEH KANANI H.; SAADAT NIAKI A.

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Journal: Researcher Bulletin of Medical Sciences Year:2001 | Volume:6 | Issue:3 (23) Page(s): 259-264

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Title

COMPARING THE EFFECTS OF MINIDOSAGE OF MARCAIN-PHENTANYL AND ROUTINE INTRATHECAL DOSAGE OF MARCAIN ON HEMODYNAMIC CHANGES DURING TURP SURGERY

Author(s)

BAGHERZADI K. | KOUZEH KANANI H. | SAADAT NIAKI A. | Issue Writer Certificate

Keywords

PHENTANYL

MARCAIN

HEMODYNAMIC CHANGES

Abstract

Background: Regarding the various known and unknown complications of drugs such as MARCAIN, and reports of similar efficacy of minidosage of MARCAIN in spinal anbsthesia in old patients, the present study was conducted over the patients referring to Shohada Tajrish hospital in 1999 with the aim of comparing the effects of minidosage of MARCAIN-PHENTANYL and routine intrathecal dosage of MARCAIN on HEMODYNAMIC CHANGES during TURP surgery. Materials and methods: This clinical trial was carried out over 50 patients candidated for TURP. Patients underwent standard spinal anesthesia and surgery. They have been randomly divided in two groups of control (routine dosa~e of MARCAIN) and case (minidosage of MARCAIN-PHENTANYL). The effects of these two regimens were assessed over the blood pressure and heart rate. Finally, HEMODYNAMIC CHANGES were analyzed. Results: Groups were matched according to the age and other influencing factors on hemodynamic indices. Alteration in diastolic blood pressure was 1.26±0.3 and 1.74±0.5 mmHg in the control and case group, respectively (N.s). These changes in the systolic blood pressure were 1.26±0.3 and 1.74±0.5 mmHg, respectively. Heart rate reduction was repolied 2.59±1.3 and 3.15±0.7 beats/min in the control and case group, respectively (p<0.05), of course these differences were not statistically significant. Complications were more or less the same in both groups. Itching was not reported in the control group, whereas, 24% of the patients in the case group were suffering from itching (p<0.01). Hypertension and hypotension were the same between the groups. Level of sensory block was more than the required level in the control group (p<0.001), meanwhile, level of motor block was complete in the control group, but incomplete in the case group (p<1.0001). 18.8±9.5 mg of ephedrine was used for the control group and 12.5±6 mg for the case group (p<0.01). Conclusion: Hemodynamic reduction and its CNS and cardiovascular complications are among the most common complications of spinal anesthesia in old patients. Results have revealed no significant HEMODYNAMIC CHANGES, so spinal anesthesia using minidosage of MARCAIN-PHENTANYL is strongly recommended for lower limb and lower abdomen surgeries in patients over 65 years old.

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APA: Copy

BAGHERZADI, K., KOUZEH KANANI, H., & SAADAT NIAKI, A.. (2001). COMPARING THE EFFECTS OF MINIDOSAGE OF MARCAIN-PHENTANYL AND ROUTINE INTRATHECAL DOSAGE OF MARCAIN ON HEMODYNAMIC CHANGES DURING TURP SURGERY. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 6(3 (23)), 259-264. SID. https://sid.ir/paper/530927/en

Vancouver: Copy

BAGHERZADI K., KOUZEH KANANI H., SAADAT NIAKI A.. COMPARING THE EFFECTS OF MINIDOSAGE OF MARCAIN-PHENTANYL AND ROUTINE INTRATHECAL DOSAGE OF MARCAIN ON HEMODYNAMIC CHANGES DURING TURP SURGERY. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2001;6(3 (23)):259-264. Available from: https://sid.ir/paper/530927/en

IEEE: Copy

K. BAGHERZADI, H. KOUZEH KANANI, and A. SAADAT NIAKI, “COMPARING THE EFFECTS OF MINIDOSAGE OF MARCAIN-PHENTANYL AND ROUTINE INTRATHECAL DOSAGE OF MARCAIN ON HEMODYNAMIC CHANGES DURING TURP SURGERY,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 6, no. 3 (23), pp. 259–264, 2001, [Online]. Available: https://sid.ir/paper/530927/en

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