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Information Journal Paper

Title

THE EFFECT OF ASCORBIC ACID ON SPATIAL LEARNING

Pages

  3-8

Abstract

 Background: ASCORBIC ACID with low & high density has agonistic & antiagonistic effects on both dopaminergic & glutamatergic systems respectively. These two systems directly affect learning & memory.Objective: To determine the effect of ASCORBIC ACID on SPATIAL LEARNING.Methods: Through an experimental study (Qazvin 1998) male rats (220-280 gr) were trained in- an 8-arms radial maze apparatus. Ascorbate (100, 500, 1000 mg/kg, I.P) was injected to the subjects & some rats received ascorbate (4,8 ug/ul) that were injected into Ventral Tegmental Area (VTA).Findings: The injection of Ascorbate (100-500 mg/kg LP) facilitates SPATIAL LEARNING dose-dependently but 1000 mg/kg of Ascorbate impairs it. The injection of 4ug/ul of Ascorbate into VTA facilitates SPATIAL LEARNING whereas injection of 8ug/ul of Ascorbate impairs it.Conclusion: Ascorbate facilitates SPATIAL LEARNING when used with low or average dose and conversely impairs it when used with high dose.

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    APA: Copy

    ESMAILI, M.H., SHARIFI, M., & DOODANGEH, E.. (2003). THE EFFECT OF ASCORBIC ACID ON SPATIAL LEARNING. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), -(24), 3-8. SID. https://sid.ir/paper/538789/en

    Vancouver: Copy

    ESMAILI M.H., SHARIFI M., DOODANGEH E.. THE EFFECT OF ASCORBIC ACID ON SPATIAL LEARNING. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2003;-(24):3-8. Available from: https://sid.ir/paper/538789/en

    IEEE: Copy

    M.H. ESMAILI, M. SHARIFI, and E. DOODANGEH, “THE EFFECT OF ASCORBIC ACID ON SPATIAL LEARNING,” JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), vol. -, no. 24, pp. 3–8, 2003, [Online]. Available: https://sid.ir/paper/538789/en

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