RELATIONSHIP BETWEEN SEX HORMONE-BINDING GLOBULIN AND GESTATIONAL DIABETES MELLITUS

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BAYANI M.A.; MAGHBOULI Z.; HOSSEIN NEZHAD A.; RAHMANI M.; ARDESHIR LARIJANI MOHAMMAD BAGHER; KETABCHI A.

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Journal: Iranian Journal of Diabetes and Metabolism Year:2006 | Volume:5 | Issue:4 Page(s): 325-330

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Title

RELATIONSHIP BETWEEN SEX HORMONE-BINDING GLOBULIN AND GESTATIONAL DIABETES MELLITUS

Author(s)

Keywords

SHBGQ3

GESTATIONAL DIABETESQ2

INSULIN RESISTANCEQ2

Abstract

Background: GESTATIONAL DIABETES mellitus is a common metabolic disorder in pregnancy. Low levels of sex hormone–binding globulin level (SHBG) are associated with increased INSULIN RESISTANCE and hyperinsulinemia. The aim of this study was comparison of SHBG levels between gestational diabetic pregnant women and normal ones. Methods: Serum SHBG concentration were measured in 38 women with GESTATIONAL DIABETES and in 143 women with normal pregnancy. The levels of Insulin, C-peptide and testosterone were measured and INSULIN RESISTANCE was estimated via HOMA Index. Insulin sensitivity was estimated via QUIKE Index. Results: Serum SHBG concentrations was significantly lower in the diabetic group (P=0.015). In a logistic regression model after adjustment of age, body mass index (BMI) and number of gravid, lower than 25 percentile of SHBG was independently effective in prediction of GESTATIONAL DIABETES mellitus.Conclusion: SHBG concentrations are lower in gestational diabetic pregnant women and low levels account as a predictor of GESTATIONAL DIABETES mellitus.

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APA: Copy

BAYANI, M.A., MAGHBOULI, Z., HOSSEIN NEZHAD, A., RAHMANI, M., ARDESHIR LARIJANI, MOHAMMAD BAGHER, & KETABCHI, A.. (2006). RELATIONSHIP BETWEEN SEX HORMONE-BINDING GLOBULIN AND GESTATIONAL DIABETES MELLITUS. JOURNAL OF DIABETES AND METABOLIC DISORDERS, 5(4), 325-330. SID. https://sid.ir/paper/54052/en

Vancouver: Copy

BAYANI M.A., MAGHBOULI Z., HOSSEIN NEZHAD A., RAHMANI M., ARDESHIR LARIJANI MOHAMMAD BAGHER, KETABCHI A.. RELATIONSHIP BETWEEN SEX HORMONE-BINDING GLOBULIN AND GESTATIONAL DIABETES MELLITUS. JOURNAL OF DIABETES AND METABOLIC DISORDERS[Internet]. 2006;5(4):325-330. Available from: https://sid.ir/paper/54052/en

IEEE: Copy

M.A. BAYANI, Z. MAGHBOULI, A. HOSSEIN NEZHAD, M. RAHMANI, MOHAMMAD BAGHER ARDESHIR LARIJANI, and A. KETABCHI, “RELATIONSHIP BETWEEN SEX HORMONE-BINDING GLOBULIN AND GESTATIONAL DIABETES MELLITUS,” JOURNAL OF DIABETES AND METABOLIC DISORDERS, vol. 5, no. 4, pp. 325–330, 2006, [Online]. Available: https://sid.ir/paper/54052/en

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