THE STUDY OF GONADOTROPIN-RELEASING HORMONE AGONIST TREATMENT OF CENTRAL PRECOCIOUS PUBERTY, SECONDARY SEXUAL CHARACTERISTICS, HEIGHT AND WEIGHT VELOCITY

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VAKILI R.

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Journal Paper

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Journal: MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES Year:2003 | Volume:46 | Issue:81 Page(s): 55-59

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Title

THE STUDY OF GONADOTROPIN-RELEASING HORMONE AGONIST TREATMENT OF CENTRAL PRECOCIOUS PUBERTY, SECONDARY SEXUAL CHARACTERISTICS, HEIGHT AND WEIGHT VELOCITY

Author(s)

VAKILI R. | Issue Writer Certificate

Keywords

TRUE PRECOCIOUS PUBERTY

GNRH AGONIST

HEIGHT AND WEIGHT VELOCITY

Abstract

Introduction: TRUE PRECOCIOUS PUBERTY (TPP) is caused by early maturation of hypothalamic GnRH secretion, and much more common in girls than in boys. In these patients psychological disturbance and inadequate final height are the major problem.Method: this studied causes, changes in secondary sexual characteristics, HEIGHT AND WEIGHT VELOCITY in 34 patients with TPP that treated with GNRH AGONIST. In this study used Chi-Square and Mann-Whitney U tests for statistical analysis.Result: Three out of 5 boys had neurogenic tumor (hamartoma, Astrocytoma, Neurofibromatosis) and 27 out of29 girls had idiopathic TPP. Treatment with GnRH analogues produced a prepubertal height velocity and reduction of secondary sexual characteristics, but weight gaining do not reduced and significantly (P<0.01) heighr than normal (4.52kg/year versus 1.52kg/year). Conclusion: We concluded that the outcome of our treatment with GNRH AGONIST depots was more effective on. reducing the height velocity and caused considerable regression in secondary sexual characteristics but we observed that it couldn't prevent patients becoming obese.

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APA: Copy

VAKILI, R.. (2003). THE STUDY OF GONADOTROPIN-RELEASING HORMONE AGONIST TREATMENT OF CENTRAL PRECOCIOUS PUBERTY, SECONDARY SEXUAL CHARACTERISTICS, HEIGHT AND WEIGHT VELOCITY. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 46(81), 55-59. SID. https://sid.ir/paper/542915/en

Vancouver: Copy

VAKILI R.. THE STUDY OF GONADOTROPIN-RELEASING HORMONE AGONIST TREATMENT OF CENTRAL PRECOCIOUS PUBERTY, SECONDARY SEXUAL CHARACTERISTICS, HEIGHT AND WEIGHT VELOCITY. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2003;46(81):55-59. Available from: https://sid.ir/paper/542915/en

IEEE: Copy

R. VAKILI, “THE STUDY OF GONADOTROPIN-RELEASING HORMONE AGONIST TREATMENT OF CENTRAL PRECOCIOUS PUBERTY, SECONDARY SEXUAL CHARACTERISTICS, HEIGHT AND WEIGHT VELOCITY,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 46, no. 81, pp. 55–59, 2003, [Online]. Available: https://sid.ir/paper/542915/en

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