EFFECT OF LOCALLY DELIVERED XANTHAN-BASED CHLO-SITE GEL ALONG WITH SCALING AND ROOT PLANNING ON REDUCTION OF GINGIVAL POCKET MICROBIAL COUNTS

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ABRISHAMI M.R.; AIRAMLOU B.; ESLAMI GITA; AKBARZADEH BAGHBAN A.R.

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Paper Information

Journal: JOURNAL OF ISLAMIC DENTAL ASSOCIATION OF IRAN (MAJALLAH-I-DANDANPIZISHKI) Year:2008 | Volume:20 | Issue:3 (68) Page(s): 199-206

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Title

EFFECT OF LOCALLY DELIVERED XANTHAN-BASED CHLO-SITE GEL ALONG WITH SCALING AND ROOT PLANNING ON REDUCTION OF GINGIVAL POCKET MICROBIAL COUNTS

Author(s)

ABRISHAMI M.R. | AIRAMLOU B. | ESLAMI GITA | AKBARZADEH BAGHBAN A.R. | Issue Writer Certificate

Keywords

P53 PROTEINQ2

KI67 ANTIGENQ3

ORAL LEUKOPLAKIAQ3

IMMUNOHISTOCHEMISTRYQ3

STAININGQ3

Abstract

Background and Aim: The locally delivered antibiotics are used as adjunct therapy together with scaling and root planning for periodontitis conditions. The aim of this study was to evaluate the microbiological effectiveness of locally delivered xanthan-based CHLO-SITE gel as an addition to scaling and root planning in treatment of cases with moderate to advanced chronic periodontitis. Materials and Methods: A randomized controlled split-mouth clinical trial method was used in this investigation. A total of 20 subjects were recruited from patients referring to dental clinics at the School of Dentistry, Shaheed Beheshti University of Medical Sciences. These cases were all met by the study’s inclusion criteria. Participation was voluntary and consent forms were obtained prior to study initiation. One quadrant with pocket depth of 4-6 mm was assigned as the experimental site and the opposite quadrant with similar condition selected as control randomly. After scaling and root planning on both sides, the CHLO-SITE, a xanthan-based gel was injected into the gingiva of the experimental sites. The pocket samples were taken from both sides at baseline, 1 and 3 months after treatment initiation. The samples were exposed to MacConkey, blood agar and nutrient agar mediums and colony counts (CC) were determined. The data were analyzed using Wilcoxon Signed Rank and Friedman tests. Results: At baseline, the CC of the experimental and control sites were 2690000 and 2645000 respectively with no significant difference. At 1 month follow up, the CC was 13850 and 151610 at experimental and control sites respectively with a significant difference (p<0.027). The CC was 13400 at experimental sites, while it was 143555 at control sites after 3 months follow up. The difference between the two groups was statistically significant as well (p<0.05). This observation showed intensive CC reduction during the first follow up period, while the decrease was slightly less after 3 months follow up. Conclusion: Based on the results of this investigation, it was revealed that, subgingival injection of xanthan-based CHLO-SITE gel after scaling and root planning in patients with chronic periodontitis, may cause significant decrease in the colony counts compared with scaling and root planning alone.

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APA: Copy

ABRISHAMI, M.R., AIRAMLOU, B., ESLAMI, GITA, & AKBARZADEH BAGHBAN, A.R.. (2008). EFFECT OF LOCALLY DELIVERED XANTHAN-BASED CHLO-SITE GEL ALONG WITH SCALING AND ROOT PLANNING ON REDUCTION OF GINGIVAL POCKET MICROBIAL COUNTS. JOURNAL OF IRANIAN DENTAL ASSOCIATION (JIDA) (MAJALLAH-I-DANDANPIZISHKI), 20(3 (68)), 199-206. SID. https://sid.ir/paper/54772/en

Vancouver: Copy

ABRISHAMI M.R., AIRAMLOU B., ESLAMI GITA, AKBARZADEH BAGHBAN A.R.. EFFECT OF LOCALLY DELIVERED XANTHAN-BASED CHLO-SITE GEL ALONG WITH SCALING AND ROOT PLANNING ON REDUCTION OF GINGIVAL POCKET MICROBIAL COUNTS. JOURNAL OF IRANIAN DENTAL ASSOCIATION (JIDA) (MAJALLAH-I-DANDANPIZISHKI)[Internet]. 2008;20(3 (68)):199-206. Available from: https://sid.ir/paper/54772/en

IEEE: Copy

M.R. ABRISHAMI, B. AIRAMLOU, GITA ESLAMI, and A.R. AKBARZADEH BAGHBAN, “EFFECT OF LOCALLY DELIVERED XANTHAN-BASED CHLO-SITE GEL ALONG WITH SCALING AND ROOT PLANNING ON REDUCTION OF GINGIVAL POCKET MICROBIAL COUNTS,” JOURNAL OF IRANIAN DENTAL ASSOCIATION (JIDA) (MAJALLAH-I-DANDANPIZISHKI), vol. 20, no. 3 (68), pp. 199–206, 2008, [Online]. Available: https://sid.ir/paper/54772/en

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