EFFECTS OF DIFFERENT GROWTH FACTORS ON NEW BONE FORMATION: A SYSTEMATIC REVIEW

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BEHNIA H.; KHOJASTEH A.; ESMAEELINEJAD M.; NAGHDI N.

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Journal: JOURNAL OF ISLAMIC DENTAL ASSOCIATION OF IRAN (MAJALLAH-I-DANDANPIZISHKI) Year:2012 | Volume:24 | Issue:2 (83) Page(s): 150-167

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Title

EFFECTS OF DIFFERENT GROWTH FACTORS ON NEW BONE FORMATION: A SYSTEMATIC REVIEW

Author(s)

BEHNIA H. | KHOJASTEH A. | ESMAEELINEJAD M. | NAGHDI N. | Issue Writer Certificate

Keywords

GROWTH FACTORSQ3

BONE REGENERATIONQ2

NEW BONE FORMATIONQ2

CARRIERQ2

BMPQ2

Abstract

Background and Aim: Using different osteogenic GROWTH FACTORS, which is still under investigation, is a favorable method for BONE REGENERATION. This systematic review is aimed at evaluating the effects of different GROWTH FACTORS and their CARRIERs on osteogenesis.Materials and Methods: Electronic databases (Medline, EMBase and Cochrane) were searched by the authors for articles published from 1999 to April 2010. Clinical and animal studies evaluating bone formation by applying a specific growth factor and the related CARRIER were included in this investigation. Obtained data were organized in a table and evaluated through a qualitative analysis.Results: Sixty-three studies most of which evaluated the effects of BMP-2 osteogenesis in different models were included in this study. Totally, twenty-five CARRIERs were applied with different GROWTH FACTORS in the experiments. Among these CARRIERs, poly lactic-co glycolic acid (PLGA), hydroxy apatite/tricalcium phosphate/absorbable collagen sponge (HA/TCP/ACS) and BioOss were the most frequently used CARRIERs with the GROWTH FACTORS in BONE REGENERATION studies.Conclusion: The current evidence, although not strong enough, confirms that BMP-2 has more favorable results in osteogenesis compared with other factors. The CARRIER scaffold, methods of measurement (histologic or radiographic), type of animal, defect diameter and the length of follow-up are the variables that should be matched before reaching definite results for the effect of GROWTH FACTORS in BONE REGENERATION.

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APA: Copy

BEHNIA, H., KHOJASTEH, A., ESMAEELINEJAD, M., & NAGHDI, N.. (2012). EFFECTS OF DIFFERENT GROWTH FACTORS ON NEW BONE FORMATION: A SYSTEMATIC REVIEW. JOURNAL OF IRANIAN DENTAL ASSOCIATION (JIDA) (MAJALLAH-I-DANDANPIZISHKI), 24(2 (83)), 150-167. SID. https://sid.ir/paper/55143/en

Vancouver: Copy

BEHNIA H., KHOJASTEH A., ESMAEELINEJAD M., NAGHDI N.. EFFECTS OF DIFFERENT GROWTH FACTORS ON NEW BONE FORMATION: A SYSTEMATIC REVIEW. JOURNAL OF IRANIAN DENTAL ASSOCIATION (JIDA) (MAJALLAH-I-DANDANPIZISHKI)[Internet]. 2012;24(2 (83)):150-167. Available from: https://sid.ir/paper/55143/en

IEEE: Copy

H. BEHNIA, A. KHOJASTEH, M. ESMAEELINEJAD, and N. NAGHDI, “EFFECTS OF DIFFERENT GROWTH FACTORS ON NEW BONE FORMATION: A SYSTEMATIC REVIEW,” JOURNAL OF IRANIAN DENTAL ASSOCIATION (JIDA) (MAJALLAH-I-DANDANPIZISHKI), vol. 24, no. 2 (83), pp. 150–167, 2012, [Online]. Available: https://sid.ir/paper/55143/en

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