COMPARISON OF PROPOFOL AND REMIFENTANIL ADMINISTRATION ON LIPID PROFILE

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FADAEIZADEH L.; RADPEY B.A.Z.; MOHAMMAD TAHERI Z.; BOU ALHASANI A.; SHAHSAVARI FATEMEH; MOUSAVI FATEMEH

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Journal: TANAFFOS Year:2007 | Volume:6 | Issue:4 Page(s): 31-36

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Title

COMPARISON OF PROPOFOL AND REMIFENTANIL ADMINISTRATION ON LIPID PROFILE

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Keywords

PROPOFOL

LIPID PROFILE

TRIGLYCERIDE

CHOLESTEROL

REMIFENTANIL

Abstract

Background: This study aimed to investigate the serum level of TRIGLYCERIDE, CHOLESTEROL, high density lipoprotein, low density lipoprotein, and very low density lipoprotein during administration of PROPOFOL and comparing it with infusion of REMIFENTANIL in patients undergoing sedation in ICU of Masih Daneshvari Hospital during 2005-2007.Materials and Methods: All patients with pulmonary disease, undergoing intubation and mechanical ventilation were enrolled in our study. The patients were randomly divided into two groups, first receiving PROPOFOL and second receiving REMIFENTANIL as the sedative agent. LIPID PROFILE griglyceride, CHOLESTEROL, high density lipoprotein, low density lipoprotein, and very low density Iipoprotein9 was checked before, immediately after, and the day after drug administration.Results: A total of 40 patients were enrolled in this study, 20 of which took PROPOFOL and the remaining took REMIFENTANIL. The mean age of the patients was 58.67±18.57 yrs. TRIGLYCERIDE and very low density lipoprotein9VLDL9 were the two factors with statistically significant rise after infusion of PROPOFOL 9p<0.0029. Such a change was not detected irtheremifentanil group. The other understudy factors did not show similar changes.Conclusion: PROPOFOL infusion can induce dramatic rises in TRIGLYCERIDE and VLDL concentration even after low dose infusions and therefore special attention must be paid to patients prone to hyper-triglyceridemia and pancreatitis.

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APA: Copy

FADAEIZADEH, L., RADPEY, B.A.Z., MOHAMMAD TAHERI, Z., BOU ALHASANI, A., SHAHSAVARI, FATEMEH, & MOUSAVI, FATEMEH. (2007). COMPARISON OF PROPOFOL AND REMIFENTANIL ADMINISTRATION ON LIPID PROFILE. TANAFFOS, 6(4), 31-36. SID. https://sid.ir/paper/554718/en

Vancouver: Copy

FADAEIZADEH L., RADPEY B.A.Z., MOHAMMAD TAHERI Z., BOU ALHASANI A., SHAHSAVARI FATEMEH, MOUSAVI FATEMEH. COMPARISON OF PROPOFOL AND REMIFENTANIL ADMINISTRATION ON LIPID PROFILE. TANAFFOS[Internet]. 2007;6(4):31-36. Available from: https://sid.ir/paper/554718/en

IEEE: Copy

L. FADAEIZADEH, B.A.Z. RADPEY, Z. MOHAMMAD TAHERI, A. BOU ALHASANI, FATEMEH SHAHSAVARI, and FATEMEH MOUSAVI, “COMPARISON OF PROPOFOL AND REMIFENTANIL ADMINISTRATION ON LIPID PROFILE,” TANAFFOS, vol. 6, no. 4, pp. 31–36, 2007, [Online]. Available: https://sid.ir/paper/554718/en

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