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Information Journal Paper

Title

HYPOGLYCEMIC EFFECT OF ETHANOLIC EXTRACT OF CARUM CARVI L. SEEDS IN NORMAL AND STREPTOZOTOCIN-INDUCED DIABETIC RATS

Pages

  106-113

Abstract

 Background: Herbal medicine has been used for many years by different cultures around the world for the treatment of DIABETES.Objective: The hypoglycemic effect of CARAWAY ethanolic extract (Carum carvi L.) was investigated in normal and STREPTOZOTOCIN-induced diabetic RATs.Methods: Intraperitoneal administration of CARAWAY ethanolic extract seeds (0.1, 0.2, 0.4 and 0.6 g/kg body wt.) on the level of serum glucose and insulin in normal and STREPTOZOTOCIN-induced diabetic RATs were evaluated. Before administration and 1, 3 and 5 h after administrations of the ethanolic extract, blood samples were drawn from the retro-orbital sinus. Serum glucose and insulin levels were determined.Results: The results showed that the CARAWAY ethanolic extract seeds at doses 0.2, 0.4 and 0.6 g/kg body wt. significantly decreased serum glucose and insulin in diabetic RATs in 3 and 5 h but not in healthy RATs.Conclusions: It could be proofed that the traditional use of CARAWAY as a hypoglycemic agent is justified and that extract from this plant show a dose-dependent hypoglycemic activity.

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    Cite

    APA: Copy

    EYDI, A., EYDI, M., HAERI ROUHANI, SEYED ALI, & BASATI, F.. (2010). HYPOGLYCEMIC EFFECT OF ETHANOLIC EXTRACT OF CARUM CARVI L. SEEDS IN NORMAL AND STREPTOZOTOCIN-INDUCED DIABETIC RATS. JOURNAL OF MEDICINAL PLANTS, 9(35), 106-113. SID. https://sid.ir/paper/556634/en

    Vancouver: Copy

    EYDI A., EYDI M., HAERI ROUHANI SEYED ALI, BASATI F.. HYPOGLYCEMIC EFFECT OF ETHANOLIC EXTRACT OF CARUM CARVI L. SEEDS IN NORMAL AND STREPTOZOTOCIN-INDUCED DIABETIC RATS. JOURNAL OF MEDICINAL PLANTS[Internet]. 2010;9(35):106-113. Available from: https://sid.ir/paper/556634/en

    IEEE: Copy

    A. EYDI, M. EYDI, SEYED ALI HAERI ROUHANI, and F. BASATI, “HYPOGLYCEMIC EFFECT OF ETHANOLIC EXTRACT OF CARUM CARVI L. SEEDS IN NORMAL AND STREPTOZOTOCIN-INDUCED DIABETIC RATS,” JOURNAL OF MEDICINAL PLANTS, vol. 9, no. 35, pp. 106–113, 2010, [Online]. Available: https://sid.ir/paper/556634/en

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