CROSS-LINKING OF CORNEAL COLLAGEN WITH UVA AND RIBOFLAVIN FOR THE TREATMENT OF CORNEAL DISEASE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HAFEZI FARHAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF CURRENT OPHTHALMOLOGY Year:2009 | Volume:21 | Issue:2 Page(s): 3-12

Download Full-Text

View:

302

Download:

120

Cites:

Information Journal Paper

Title

CROSS-LINKING OF CORNEAL COLLAGEN WITH UVA AND RIBOFLAVIN FOR THE TREATMENT OF CORNEAL DISEASE

Author(s)

HAFEZI FARHAD | Issue Writer Certificate

Keywords

COLLAGEN

CROSS-LINKING

ULTRAVIOLET A

RIBOFLAVIN

KERATOCONUS

PELLUCID MARGINAL DEGENERATION

IATROGENIC KERATECTASIA

Abstract

Introduction: In recent years, reduced corneal biomechanics have been identified as an important element in the pathogenesis of various corneal diseases. The biomechanical characteristics of a connective tissue such as strength and resistance against mechanical stress are indispensable prerequisites to maintain regular shape and function of that tissue. Intra- and intermolecular cross-links between COLLAGEN molecules are essential elements of these biomechanical properties. Accordingly, COLLAGEN cross-links occur physiologically in all organs and tissues with certain biomechanical characteristics.In other surgical fields, CROSS-LINKING has been used for decades to increase the biomechanical properties of connective tissue structures: in cardiac surgery, porcine aortic valve bioprosthesises are treated with glutaraldehyde prior to implantation to ensure increased CROSS-LINKING, which increases biomechanical resistance against biodegradation. Additionally, in otolaryngology, polymers inducing CROSS-LINKING are used in the treatment of destabilized vocal cords and for nasal reconstruction.In the cornea, a variety of conditions such as primary acquired (keratoconus and pellucid marginal corneal degeneration) and secondary induced (iatrogenic keratectasia after refractive laser surgery) ectatic disorders lead to a reduced biomechanical resistance. Corneal COLLAGEN CROSS-LINKING with RIBOFLAVIN/UVA (CXL) represents a new approach to these diseases. To assist researchers and clinicians interested in the field, this article attempts to provide a structured overview on the current state of the method, basic principles, technique, and application of CXL in primary and IATROGENIC KERATECTASIA. Furthermore, it addresses safety issues and potential complications of the method.

Cites

No record.

References

Cite

APA: Copy

HAFEZI, FARHAD. (2009). CROSS-LINKING OF CORNEAL COLLAGEN WITH UVA AND RIBOFLAVIN FOR THE TREATMENT OF CORNEAL DISEASE. JOURNAL OF CURRENT OPHTHALMOLOGY, 21(2), 3-12. SID. https://sid.ir/paper/562792/en

Vancouver: Copy

HAFEZI FARHAD. CROSS-LINKING OF CORNEAL COLLAGEN WITH UVA AND RIBOFLAVIN FOR THE TREATMENT OF CORNEAL DISEASE. JOURNAL OF CURRENT OPHTHALMOLOGY[Internet]. 2009;21(2):3-12. Available from: https://sid.ir/paper/562792/en

IEEE: Copy

FARHAD HAFEZI, “CROSS-LINKING OF CORNEAL COLLAGEN WITH UVA AND RIBOFLAVIN FOR THE TREATMENT OF CORNEAL DISEASE,” JOURNAL OF CURRENT OPHTHALMOLOGY, vol. 21, no. 2, pp. 3–12, 2009, [Online]. Available: https://sid.ir/paper/562792/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops