MYCOBACTERIAL ANTIBODIES AGAINST BCG AND M.TUBERCULOSIS H37RA DO NOT RECOGNIZE PATHOGENIC M.TUBERCULOSIS CELLS BUT DO RECOGNIZE THEIR CYTOPLASMIC CONSTITUENTS

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SHAFAGHI B.; JAR ELAHI A.; RENNOU M.; MAES R.F.; BAHREHMAND A.R.

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Journal: TANAFFOS Year:2006 | Volume:5 | Issue:4 (20) Page(s): 15-21

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Title

MYCOBACTERIAL ANTIBODIES AGAINST BCG AND M.TUBERCULOSIS H37RA DO NOT RECOGNIZE PATHOGENIC M.TUBERCULOSIS CELLS BUT DO RECOGNIZE THEIR CYTOPLASMIC CONSTITUENTS

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Keywords

VACCINATION

MYCOBACTERIUM TUBERCULOSIS

BCG

IMMUNOSUPPRESSION ANTIBODIES

Abstract

The humeral immune response against mycobacterial pathogens and BCG vaccine is still, poorly understood. It is not known if antibodies raised against BCG react with all pathogenic M. tuberculosis strains. The, question arose during the development of a tuberculosis detection system based on antibodies. It was found that antibodies raised against cells of avirulent TB strain H37Ra and against whole sonicates of BCG do not react consistently with whole cells of pathogenic TB strains and very poorly with whole BCG cells. These antibodies; however, react very well with the internal components of the BCG cell (i.e. A 60 and cytoplasmic constituents).

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APA: Copy

SHAFAGHI, B., JAR ELAHI, A., RENNOU, M., MAES, R.F., & BAHREHMAND, A.R.. (2006). MYCOBACTERIAL ANTIBODIES AGAINST BCG AND M.TUBERCULOSIS H37RA DO NOT RECOGNIZE PATHOGENIC M.TUBERCULOSIS CELLS BUT DO RECOGNIZE THEIR CYTOPLASMIC CONSTITUENTS . TANAFFOS, 5(4 (20)), 15-21. SID. https://sid.ir/paper/563835/en

Vancouver: Copy

SHAFAGHI B., JAR ELAHI A., RENNOU M., MAES R.F., BAHREHMAND A.R.. MYCOBACTERIAL ANTIBODIES AGAINST BCG AND M.TUBERCULOSIS H37RA DO NOT RECOGNIZE PATHOGENIC M.TUBERCULOSIS CELLS BUT DO RECOGNIZE THEIR CYTOPLASMIC CONSTITUENTS . TANAFFOS[Internet]. 2006;5(4 (20)):15-21. Available from: https://sid.ir/paper/563835/en

IEEE: Copy

B. SHAFAGHI, A. JAR ELAHI, M. RENNOU, R.F. MAES, and A.R. BAHREHMAND, “MYCOBACTERIAL ANTIBODIES AGAINST BCG AND M.TUBERCULOSIS H37RA DO NOT RECOGNIZE PATHOGENIC M.TUBERCULOSIS CELLS BUT DO RECOGNIZE THEIR CYTOPLASMIC CONSTITUENTS ,” TANAFFOS, vol. 5, no. 4 (20), pp. 15–21, 2006, [Online]. Available: https://sid.ir/paper/563835/en

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