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مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Title

PREVALENCE OF OSELTAMIVIR-RESISTANT 2009 H1N1 INFLUENZA VIRUS AMONG PATIENTS WITH PANDEMIC 2009 H1N1 INFLUENZA INFECTION IN NRITLD, TEHRAN, IRAN

Pages

  8-11

Abstract

 Background: Oseltamivir-resistant cases were reported during the 2009 pandemic influenza outbreak and therefore, widespread emergence of oseltamivir-resistant 2009 H1N1 virus is imaginable. Underlying medical conditions like immunosuppression increase the chance of oseltamivir resistance.Materials and Methods: In a retrospective cross-sectional study, respiratory tract specimens of confirmed cases of 2009 H1N1 influenza referred to the Masih Daneshvari Hospital were analyzed for presence of H275Y MUTATION.Results: From November 2009 through March 2010, oseltamivir- resistant 2009 H1N1 infection was observed and confirmed in 4 patients (including 2 immunocompromised patients) by performing H275Y MUTATION molecular testing.Conclusion: Close monitoring of resistance to neuraminidase inhibitors is essential in tertiary care centers. The H275Y MUTATION (oseltamivir-resistant genotype) could appear in the absence or presence of selective drug pressure.

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    APA: Copy

    MORADI, AHMADREZA, NADJI, SEYED ALIREZA, TABARSI, PAYAM, HASHEMIAN, SEYED MOHAMMADREZA, MARJANI, MAJID, SIGAROODI, AFSANEH, MANSOURI, DAVOOD, MASJEDI, MOHAMMADREZA, & VELAYATI, ALI AKBAR. (2011). PREVALENCE OF OSELTAMIVIR-RESISTANT 2009 H1N1 INFLUENZA VIRUS AMONG PATIENTS WITH PANDEMIC 2009 H1N1 INFLUENZA INFECTION IN NRITLD, TEHRAN, IRAN. TANAFFOS, 10(1), 8-11. SID. https://sid.ir/paper/571080/en

    Vancouver: Copy

    MORADI AHMADREZA, NADJI SEYED ALIREZA, TABARSI PAYAM, HASHEMIAN SEYED MOHAMMADREZA, MARJANI MAJID, SIGAROODI AFSANEH, MANSOURI DAVOOD, MASJEDI MOHAMMADREZA, VELAYATI ALI AKBAR. PREVALENCE OF OSELTAMIVIR-RESISTANT 2009 H1N1 INFLUENZA VIRUS AMONG PATIENTS WITH PANDEMIC 2009 H1N1 INFLUENZA INFECTION IN NRITLD, TEHRAN, IRAN. TANAFFOS[Internet]. 2011;10(1):8-11. Available from: https://sid.ir/paper/571080/en

    IEEE: Copy

    AHMADREZA MORADI, SEYED ALIREZA NADJI, PAYAM TABARSI, SEYED MOHAMMADREZA HASHEMIAN, MAJID MARJANI, AFSANEH SIGAROODI, DAVOOD MANSOURI, MOHAMMADREZA MASJEDI, and ALI AKBAR VELAYATI, “PREVALENCE OF OSELTAMIVIR-RESISTANT 2009 H1N1 INFLUENZA VIRUS AMONG PATIENTS WITH PANDEMIC 2009 H1N1 INFLUENZA INFECTION IN NRITLD, TEHRAN, IRAN,” TANAFFOS, vol. 10, no. 1, pp. 8–11, 2011, [Online]. Available: https://sid.ir/paper/571080/en

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