EFFICACY OF COMBINED TRIPLE THERAPY (PARAMOMYCIN OINTMENT, CRYOTHERAPY AND INTRALESIONAL GLUCANTIME) IN COMPARISON WITH INTRALESIONAL GLUCANTIME FOR THE TREATMENT OF ACUTE CUTANEOUS LEISHMANIASIS

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NILFOROUSHZADEH MOHAMMAD ALI; MALEK AFZALI BEHESHTEH; JAFARI F.

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Journal: Iranian Journal of Dermatology Year:2004 | Volume:3 | Issue:3 (27) Page(s): 136-139

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Title

EFFICACY OF COMBINED TRIPLE THERAPY (PARAMOMYCIN OINTMENT, CRYOTHERAPY AND INTRALESIONAL GLUCANTIME) IN COMPARISON WITH INTRALESIONAL GLUCANTIME FOR THE TREATMENT OF ACUTE CUTANEOUS LEISHMANIASIS

Author(s)

NILFOROUSHZADEH MOHAMMAD ALI | MALEK AFZALI BEHESHTEH | JAFARI F. | Issue Writer Certificate

Keywords

LEISHMANIASISQ3

GLUCANTIMEQ3

CRYOTHERAPYQ4

PARAMOMYCINQ4

Abstract

Background: In spite of different methods of treatment, there is not a simple, safe and complete curative treatment for cutaneous LEISHMANIASIS (CL), yet. Objective: To compare the efficacy of intralesional GLUCANTIME injection alone, with the combined triple therapy of CRYOTHERAPY, paramomycm ointment and intralesional GLUCANTIME in the treatment of CL. Patients & Methods: 157 patients with CL were randomly allocated into two groups, 81 patients in group I were injected with intralesional GLUCANTIME (twice a week up to healing of the lesions or maximum 6 weeks). 76 patients in group 2 were treated with PARAMOMYCIN ointment (15% in 10% urea, twice a day), CRYOTHERAPY (maximum 3 times 2 weeks apart and injection of intralesional GLUCANTIME (once a week), for the same period as group 1. Results: After 6 weeks, complete cure rate in group 2 (89.5%) was significantly more than group 1 (70.4%) (P<0.05). Conclusion: Our results indicating of more efficacy of the triple therapy is in accordance with the previous studies of combined CRYOTHERAPY and PARAMOMYCIN. It could be recommended as a better treatment modality for CL wherever possible.

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APA: Copy

NILFOROUSHZADEH, MOHAMMAD ALI, MALEK AFZALI, BEHESHTEH, & JAFARI, F.. (2004). EFFICACY OF COMBINED TRIPLE THERAPY (PARAMOMYCIN OINTMENT, CRYOTHERAPY AND INTRALESIONAL GLUCANTIME) IN COMPARISON WITH INTRALESIONAL GLUCANTIME FOR THE TREATMENT OF ACUTE CUTANEOUS LEISHMANIASIS. IRANIAN JOURNAL OF DERMATOLOGY, 3(3 (27)), 136-139. SID. https://sid.ir/paper/57656/en

Vancouver: Copy

NILFOROUSHZADEH MOHAMMAD ALI, MALEK AFZALI BEHESHTEH, JAFARI F.. EFFICACY OF COMBINED TRIPLE THERAPY (PARAMOMYCIN OINTMENT, CRYOTHERAPY AND INTRALESIONAL GLUCANTIME) IN COMPARISON WITH INTRALESIONAL GLUCANTIME FOR THE TREATMENT OF ACUTE CUTANEOUS LEISHMANIASIS. IRANIAN JOURNAL OF DERMATOLOGY[Internet]. 2004;3(3 (27)):136-139. Available from: https://sid.ir/paper/57656/en

IEEE: Copy

MOHAMMAD ALI NILFOROUSHZADEH, BEHESHTEH MALEK AFZALI, and F. JAFARI, “EFFICACY OF COMBINED TRIPLE THERAPY (PARAMOMYCIN OINTMENT, CRYOTHERAPY AND INTRALESIONAL GLUCANTIME) IN COMPARISON WITH INTRALESIONAL GLUCANTIME FOR THE TREATMENT OF ACUTE CUTANEOUS LEISHMANIASIS,” IRANIAN JOURNAL OF DERMATOLOGY, vol. 3, no. 3 (27), pp. 136–139, 2004, [Online]. Available: https://sid.ir/paper/57656/en

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