CERVICO-VAGINAL INVOLVEMENT AND PAPANICOLAOU SMEAR IN PEMPHIGUS VULGARIS: A CLINICAL STUDY OF 77 CASES

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AKHYANI M.; SHAMS DAVACHI SH.; SAFAEI NARAGHI Z.; DANESH PAZHOUH MARYAM; TOUSI S.; ASGARI M.; MALEK HAMI F.

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Journal: Iranian Journal of Dermatology Year:2007 | Volume:10 | Issue:3 (41) Page(s): 196-202

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Title

CERVICO-VAGINAL INVOLVEMENT AND PAPANICOLAOU SMEAR IN PEMPHIGUS VULGARIS: A CLINICAL STUDY OF 77 CASES

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Keywords

PEMPHIGUS VULGARISQ3

GENITALQ3

CERVIXQ3

PAPANICOLAOU SMEARQ3

Abstract

Background and aim: PEMPHIGUS VULGARIS (PV) is an autoimmune blistering disease which is known to involve the female GENITAL tract but the frequency at which this occurs is unknown. There are relatively few reports in the literature of the cytological appearance of PV on cervicovaginal smears. Our aim was to evaluate involvement of the female GENITAL tract and cervicovaginal Papanicolaou (Pap) smears in PV.Materials and methods: The study included 77 patients with PV visited from April 2005to February 2007. Each patient was subjected to gynecological examination and cervicovaginal Pap smear. Results: The mean age of patients was 44.7±13 years. GENITAL lesions were observed in 39 patients (50.6%).Labia minor was involved in 36 patients (92.3%), while labia major in 11(28.2%), vagina in 14 (35.8%), and CERVIX in six (15.3%). Cervicovaginal smears of 20 patients (25.9%) showed PV. Among 72 satisfactory smears, cervical Pap smears were normal in 25 patients (34.7%), inflammatory in 43 patients (59.7%), and dysplastic (low-grade cervical intra-epithelial neoplasia [CIN I] in four patients (5.5%). In 2 of these patients, Pap smears were normal repeated when patients were in remission.Conclusion: Involvement of the female GENITAL tract might not be as infrequent as was previously thought and it is probably the second most common mucosal site of PV after oral mucosa. GENITAL lesions maybe missed and the need for thorough pelvic examination shouldn't be overlooked.

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APA: Copy

AKHYANI, M., SHAMS DAVACHI, SH., SAFAEI NARAGHI, Z., DANESH PAZHOUH, MARYAM, TOUSI, S., ASGARI, M., & MALEK HAMI, F.. (2007). CERVICO-VAGINAL INVOLVEMENT AND PAPANICOLAOU SMEAR IN PEMPHIGUS VULGARIS: A CLINICAL STUDY OF 77 CASES. IRANIAN JOURNAL OF DERMATOLOGY, 10(3 (41)), 196-202. SID. https://sid.ir/paper/57714/en

Vancouver: Copy

AKHYANI M., SHAMS DAVACHI SH., SAFAEI NARAGHI Z., DANESH PAZHOUH MARYAM, TOUSI S., ASGARI M., MALEK HAMI F.. CERVICO-VAGINAL INVOLVEMENT AND PAPANICOLAOU SMEAR IN PEMPHIGUS VULGARIS: A CLINICAL STUDY OF 77 CASES. IRANIAN JOURNAL OF DERMATOLOGY[Internet]. 2007;10(3 (41)):196-202. Available from: https://sid.ir/paper/57714/en

IEEE: Copy

M. AKHYANI, SH. SHAMS DAVACHI, Z. SAFAEI NARAGHI, MARYAM DANESH PAZHOUH, S. TOUSI, M. ASGARI, and F. MALEK HAMI, “CERVICO-VAGINAL INVOLVEMENT AND PAPANICOLAOU SMEAR IN PEMPHIGUS VULGARIS: A CLINICAL STUDY OF 77 CASES,” IRANIAN JOURNAL OF DERMATOLOGY, vol. 10, no. 3 (41), pp. 196–202, 2007, [Online]. Available: https://sid.ir/paper/57714/en

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