TREATMENT OF CUTANEOUS LEISHMANIASIS WITH 5% GARLIC CREAM:A RANDOMIZED, DOUBLE-BLIND STUDY

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GHOLAMI A.R.; KHAMESIPOUR A.; MOMENI A.; GHAZANFARI T.; NILFOROUSHZADEH MOHAMMAD ALI; DARAJEH Z.; DOULATI Y.

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Journal: Iranian Journal of Dermatology Year:2000 | Volume:3 | Issue:3 (11) Page(s): 2-6

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Title

TREATMENT OF CUTANEOUS LEISHMANIASIS WITH 5% GARLIC CREAM:A RANDOMIZED, DOUBLE-BLIND STUDY

Author(s)

Keywords

CUTANEOUS LEISHMANIASISQ3

GARLICQ4

TREATMENTQ3

Abstract

Background: CUTANEOUS LEISHMANIASIS (CL) is a protozoan disease of the skin caused by a wide range of italic species. The disease is endemic in many countries. It has been recognized as a major public health problem in Iran. Much TREATMENT has been suggested for it but none of them was fully effective. Objective: The objective of this study was to compare the efficacy of a 5% GARLIC cream with placebo in CL. Patients & Methods: A double blind, placebo controlled study was performed in Isfahan and Jahrom in 1997 and 1998. 197 patients were randomly selected. Exclusion criteria were: pregnancy, lactation, age less than 5 years and duration of disease more than 100 days. Each patient received GARLIC cream 5% or placebo for 3 weeks and was followed for another period of 40 days. Results: The study was completed as planned in 171 patients. 96 were treated with GARLIC 5% cream and 75 with placebo. Complete healing occurred in 18 (18.75%) of GARLIC group in comparison with 15 (20%) of placebo group. The difference was not significant. (PV =0/9865) Conclusion: 5% GARLIC cream was not effective in TREATMENT of CUTANEOUS LEISHMANIASIS. Further studies with higher concentrations or different vehicle are needed.

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APA: Copy

GHOLAMI, A.R., KHAMESIPOUR, A., MOMENI, A., GHAZANFARI, T., NILFOROUSHZADEH, MOHAMMAD ALI, DARAJEH, Z., & DOULATI, Y.. (2000). TREATMENT OF CUTANEOUS LEISHMANIASIS WITH 5% GARLIC CREAM:A RANDOMIZED, DOUBLE-BLIND STUDY. IRANIAN JOURNAL OF DERMATOLOGY, 3(3 (11)), 2-6. SID. https://sid.ir/paper/57763/en

Vancouver: Copy

GHOLAMI A.R., KHAMESIPOUR A., MOMENI A., GHAZANFARI T., NILFOROUSHZADEH MOHAMMAD ALI, DARAJEH Z., DOULATI Y.. TREATMENT OF CUTANEOUS LEISHMANIASIS WITH 5% GARLIC CREAM:A RANDOMIZED, DOUBLE-BLIND STUDY. IRANIAN JOURNAL OF DERMATOLOGY[Internet]. 2000;3(3 (11)):2-6. Available from: https://sid.ir/paper/57763/en

IEEE: Copy

A.R. GHOLAMI, A. KHAMESIPOUR, A. MOMENI, T. GHAZANFARI, MOHAMMAD ALI NILFOROUSHZADEH, Z. DARAJEH, and Y. DOULATI, “TREATMENT OF CUTANEOUS LEISHMANIASIS WITH 5% GARLIC CREAM:A RANDOMIZED, DOUBLE-BLIND STUDY,” IRANIAN JOURNAL OF DERMATOLOGY, vol. 3, no. 3 (11), pp. 2–6, 2000, [Online]. Available: https://sid.ir/paper/57763/en

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