A COMPARISON BETWEEN SYSTEMIC PUVA THERAPY ALONE AND COMBINED WITH TOPICAL CALCIPORIOL IN THE TREATMENT OF GENERALIZED VITILIGO

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AKHYANI M.; HALAJI Z.; EHSANI A.H.; MOKARRAMI T.; GOROUHI F.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Dermatology Year:2005 | Volume:8 | Issue:3 Page(s): 171-176

Download Full-Text

Persian Verion

View:

1,267

Download:

Cites:

Information Journal Paper

Title

A COMPARISON BETWEEN SYSTEMIC PUVA THERAPY ALONE AND COMBINED WITH TOPICAL CALCIPORIOL IN THE TREATMENT OF GENERALIZED VITILIGO

Author(s)

Keywords

VITILIGOQ3

PUVAQ4

CA1CIPOTRIOLQ4

METHOXALENQ3

Abstract

Background: VITILIGO is a relatively common acquired depigmentary disorder affecting approximately 1 % of general population. PUVA therapy is the most effective modality and commonly used as the primary treatment of generalized VITILIGO. Objective: To evaluate the synergistic effect of topical calcipotriol and oral METHOXALENe plus PUVA in treatment of generalized VITILIGO. Patients and Methods: In this clinical trial, 47 patients with generalized VITILIGO(<40% involvement of skin surface area) were randomly assigned to two treatment groups. Both groups were treated with systemic PUVA three times weekly. One group was also treated with topical calcipotriol (0.005%). Patients were evaluated for treatment response and possible side effects. . Results: The mean response rate at the end of the study was 63.9%±24.1 in the calcipotriol and PUVA group and 60.6%±23 in the PUVA group (P<0.05). The number of PUVA sessions and the mean cumulative UVA dose for maximum response were 96.6±22.7 and 584.1± 118.1 J/cm2 in the calcipotriol and PUVA group and 116.3±26.1 and 685.1± 168.0 J/cm2 in the PUVA group (P<0.05). Conclusion: In patients with generalized VITILIGO, of combination PUVA with ca1cipotriol is an effective and safe treatment. This method decreases number of PUV A sessions and UVA dosage compared to treatment alone and accelerates PUVA repigmentation.

Cites

No record.

References

No record.

Cite

APA: Copy

AKHYANI, M., HALAJI, Z., EHSANI, A.H., MOKARRAMI, T., & GOROUHI, F.. (2005). A COMPARISON BETWEEN SYSTEMIC PUVA THERAPY ALONE AND COMBINED WITH TOPICAL CALCIPORIOL IN THE TREATMENT OF GENERALIZED VITILIGO. IRANIAN JOURNAL OF DERMATOLOGY, 8(3), 171-176. SID. https://sid.ir/paper/57807/en

Vancouver: Copy

AKHYANI M., HALAJI Z., EHSANI A.H., MOKARRAMI T., GOROUHI F.. A COMPARISON BETWEEN SYSTEMIC PUVA THERAPY ALONE AND COMBINED WITH TOPICAL CALCIPORIOL IN THE TREATMENT OF GENERALIZED VITILIGO. IRANIAN JOURNAL OF DERMATOLOGY[Internet]. 2005;8(3):171-176. Available from: https://sid.ir/paper/57807/en

IEEE: Copy

M. AKHYANI, Z. HALAJI, A.H. EHSANI, T. MOKARRAMI, and F. GOROUHI, “A COMPARISON BETWEEN SYSTEMIC PUVA THERAPY ALONE AND COMBINED WITH TOPICAL CALCIPORIOL IN THE TREATMENT OF GENERALIZED VITILIGO,” IRANIAN JOURNAL OF DERMATOLOGY, vol. 8, no. 3, pp. 171–176, 2005, [Online]. Available: https://sid.ir/paper/57807/en

Related Journal Papers