THE EFFICACY OF ORAL ERYTHROMYCIN IN THE TREATMENT OF PATIENTS WITH PITYRIASIS ROSEA: A RANDOMIZED
DOUBLE-BLIND, PLACEBO - CONTROLLED CLINICAL TRIAL

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AKHYANI M.; MORTAZAVI H.; IZADI M.; EHSANI A.H

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Journal: Iranian Journal of Dermatology Year:2003 | Volume:7 | Issue:1 Page(s): 14-18

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Information Journal Paper

Title

THE EFFICACY OF ORAL ERYTHROMYCIN IN THE TREATMENT OF PATIENTS WITH PITYRIASIS ROSEA: A RANDOMIZED DOUBLE-BLIND, PLACEBO - CONTROLLED CLINICAL TRIAL

Author(s)

AKHYANI M. | MORTAZAVI H. | IZADI M. | EHSANI A.H | Issue Writer Certificate

Keywords

PITYRIASIS ROSEAQ4

ERYTHROMYCINQ4

CLINICAL TRIALQ3

Abstract

Background: PITYRIASIS ROSEA is an acute, inflammatory and self- limited disease which is characterized by a primary scaly plaque (herald patch) followed by a generalized, symmetrical papulosqumous eruption (mostly on trunk and proximal extremities). Objective: To determine the efficacy of ERYTHROMYCIN in the treatment of patients with PITYRIASIS ROSEA. Patients & Methods: In this double- blind randomized CLINICAL TRIAL, 46 patients with PITYRIASIS ROSEA in two equal groups were treated with oral ERYTHROMYCIN 1gr per day or placebo for seven days and were followed 1,2 and 6 weeks after treatment. The response to the treatment was evaluated as complete, partial and no response. Results: In 48% of the case group and 13% of the control group complete response was seen at the end of first week of treatment. Moreover, these rates reached 91%and 57% at the end of second week, 100% and 87% at the end of sixth week, respectively. The differences between two groups were statistically significant after first and second weeks. Conclusion: Oral ERYTHROMYCIN was effective in the treatment of patients with PITYRIASIS ROSEA. Also, it reduces the duration of disease.

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APA: Copy

AKHYANI, M., MORTAZAVI, H., IZADI, M., & EHSANI, A.H. (2003). THE EFFICACY OF ORAL ERYTHROMYCIN IN THE TREATMENT OF PATIENTS WITH PITYRIASIS ROSEA: A RANDOMIZED DOUBLE-BLIND, PLACEBO - CONTROLLED CLINICAL TRIAL. IRANIAN JOURNAL OF DERMATOLOGY, 7(1), 14-18. SID. https://sid.ir/paper/57815/en

Vancouver: Copy

AKHYANI M., MORTAZAVI H., IZADI M., EHSANI A.H. THE EFFICACY OF ORAL ERYTHROMYCIN IN THE TREATMENT OF PATIENTS WITH PITYRIASIS ROSEA: A RANDOMIZED DOUBLE-BLIND, PLACEBO - CONTROLLED CLINICAL TRIAL. IRANIAN JOURNAL OF DERMATOLOGY[Internet]. 2003;7(1):14-18. Available from: https://sid.ir/paper/57815/en

IEEE: Copy

M. AKHYANI, H. MORTAZAVI, M. IZADI, and A.H EHSANI, “THE EFFICACY OF ORAL ERYTHROMYCIN IN THE TREATMENT OF PATIENTS WITH PITYRIASIS ROSEA: A RANDOMIZED DOUBLE-BLIND, PLACEBO - CONTROLLED CLINICAL TRIAL,” IRANIAN JOURNAL OF DERMATOLOGY, vol. 7, no. 1, pp. 14–18, 2003, [Online]. Available: https://sid.ir/paper/57815/en

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