EVALUATION OF THE EFFICACY OF INTERMITTENT ISOTRETINOIN DOSES IN ACNE PATIENTS

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TOUSI P.; SEDIGHHA A.; MONSHIZADEH H.; TOUSI R.

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Journal Paper

Paper Information

Journal: Iranian Journal of Dermatology Year:2005 | Volume:8 | Issue:4 (32) Page(s): 256-259

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Information Journal Paper

Title

EVALUATION OF THE EFFICACY OF INTERMITTENT ISOTRETINOIN DOSES IN ACNE PATIENTS

Author(s)

TOUSI P. | SEDIGHHA A. | MONSHIZADEH H. | TOUSI R. | Issue Writer Certificate

Keywords

ACNEQ2

ISOTRETINOINQ4

TOTAL DOSEQ4

Abstract

Background and objective: Oral ISOTRETINOIN is the only treatment that has an effect on all the major etiological factors involved in ACNE (increased sebum production, alterations in microbial flora, hyperkeratinization of pilosebaceous duct, and inflammation). Considering complications and relative expense, several treatment regimens have been suggested. The objective of this study was to evaluate the efficacy of intermittent doses of ISOTRETINOIN in ACNE patients. Materials and Methods: We made a quasi-experimental clinical trial in the ACNE patients without nodular and cystic lesions that were recalcitrant to conventional therapy. Therapeutic regimen included 0.5 mg/kg ISOTRETINOIN per day for a week every month; so we use 21 mg/kg as total dosage. Results: ACNE severity decreased in entire patients at the end of treatment course. After six months follow up, recurrence rate was 19.3% and partially recurrence rate was 44%. Conclusion: It seems that intermittent ISOTRETINOIN treatment with a TOTAL DOSE of 21 mg/kg has led to good therapeutic results in patients without nodulocystic lesions.

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APA: Copy

TOUSI, P., SEDIGHHA, A., MONSHIZADEH, H., & TOUSI, R.. (2005). EVALUATION OF THE EFFICACY OF INTERMITTENT ISOTRETINOIN DOSES IN ACNE PATIENTS. IRANIAN JOURNAL OF DERMATOLOGY, 8(4 (32)), 256-259. SID. https://sid.ir/paper/57917/en

Vancouver: Copy

TOUSI P., SEDIGHHA A., MONSHIZADEH H., TOUSI R.. EVALUATION OF THE EFFICACY OF INTERMITTENT ISOTRETINOIN DOSES IN ACNE PATIENTS. IRANIAN JOURNAL OF DERMATOLOGY[Internet]. 2005;8(4 (32)):256-259. Available from: https://sid.ir/paper/57917/en

IEEE: Copy

P. TOUSI, A. SEDIGHHA, H. MONSHIZADEH, and R. TOUSI, “EVALUATION OF THE EFFICACY OF INTERMITTENT ISOTRETINOIN DOSES IN ACNE PATIENTS,” IRANIAN JOURNAL OF DERMATOLOGY, vol. 8, no. 4 (32), pp. 256–259, 2005, [Online]. Available: https://sid.ir/paper/57917/en

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