EVALUATION OF THE EFFICACY OF DIPHENYL CYCLOPROPENONE IN THE TREATMENT OF RESISTANT WARTS

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FARNAGHI F.; SEYRAFI H.; EHSANI A.H.; TORK A.N.; YAZDANIAN SH.; ZARINNEZHAD N.

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Journal: Iranian Journal of Dermatology Year:2007 | Volume:10 | Issue:2 (40) Page(s): 94-99

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Title

EVALUATION OF THE EFFICACY OF DIPHENYL CYCLOPROPENONE IN THE TREATMENT OF RESISTANT WARTS

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Keywords

WARTQ3

TREATMENTQ3

IMMUNOTHERAPYQ3

Abstract

Background and aim: TREATMENT of resistant WARTs is a common clinical problem. IMMUNOTHERAPY with diphenyl cyclopropenone (DCP) as a contact sensitizer has been reported. The objective of this study was to evaluate the efficacy of DCP in refractory WARTs.Materials and methods: Nineteen patients with refractory WARTs referred to Razi Hospital in 2004 who had not responded to at least 2 TREATMENT modalities, were sensitized with 2% DCP in acetone. Then TREATMENT was started with application of] % DCP on plantar WARTs and 0.2% on other locations.Results: Two patients were not sensitized even after 3 attempts. Three other patients discontinued TREATMENT due to side effects (severe eczema and pruritus). Six male and 8 female patients completed the trial, among them, 10 (71.5%) showed complete clearance of WARTs. Side effects reported were: local pruritus (21%), distant eczema (10.5%), local blister (26.3%). The patients received a mean of 5 TREATMENT sessions.Conclusion: Topical IMMUNOTHERAPY with DCP is an effective TREATMENT for refractory WARTs. Due to high efficacy, no scarring, and being a painless procedure it can be considered as a first line TREATMENT of refractory WARTs.

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APA: Copy

FARNAGHI, F., SEYRAFI, H., EHSANI, A.H., TORK, A.N., YAZDANIAN, SH., & ZARINNEZHAD, N.. (2007). EVALUATION OF THE EFFICACY OF DIPHENYL CYCLOPROPENONE IN THE TREATMENT OF RESISTANT WARTS. IRANIAN JOURNAL OF DERMATOLOGY, 10(2 (40)), 94-99. SID. https://sid.ir/paper/57970/en

Vancouver: Copy

FARNAGHI F., SEYRAFI H., EHSANI A.H., TORK A.N., YAZDANIAN SH., ZARINNEZHAD N.. EVALUATION OF THE EFFICACY OF DIPHENYL CYCLOPROPENONE IN THE TREATMENT OF RESISTANT WARTS. IRANIAN JOURNAL OF DERMATOLOGY[Internet]. 2007;10(2 (40)):94-99. Available from: https://sid.ir/paper/57970/en

IEEE: Copy

F. FARNAGHI, H. SEYRAFI, A.H. EHSANI, A.N. TORK, SH. YAZDANIAN, and N. ZARINNEZHAD, “EVALUATION OF THE EFFICACY OF DIPHENYL CYCLOPROPENONE IN THE TREATMENT OF RESISTANT WARTS,” IRANIAN JOURNAL OF DERMATOLOGY, vol. 10, no. 2 (40), pp. 94–99, 2007, [Online]. Available: https://sid.ir/paper/57970/en

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