A CASE REPORT OF MALIGNANT INFANTILE OSTEOPETROSIS

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USTA MERVE; GEYLANI GULEC SEDA; KARAMAN SERAP; ERDEM ELA; EMRAL HICRAN; URGANCI NAFIYE

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Journal Paper

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Journal: Iranian Journal of Pediatrics Year:2012 | Volume:22 | Issue:3 Page(s): 421-424

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Title

A CASE REPORT OF MALIGNANT INFANTILE OSTEOPETROSIS

Author(s)

Keywords

OSTEOPETROSIS

INFANT

HEPATOMEGALY

SPLENOMEGALY

Abstract

Background: Malignant INFANTile OSTEOPETROSIS (MIOP) presents early in life with extreme sclerosis of the skeleton and reduction of bone marrow spaces. Since there is a defect in the bone marrow, the disease can cause anemia, extramedullary hematopoiesis secondary to anemia leading to hepatosplenomegaly, cranial nerves compression and severe growth failure. This disorder is often lethal within the first decade of life because of secondary infections. Stem cell transplantation (SCT) remains the only curative therapy.Case Presentation: We report a two-month old male INFANT, diagnosed as MIOP while investigating the cause of hepatosplenomegaly. The patient was referred for stem cell transplantation.Conclusion: Malignant INFANTile OSTEOPETROSIS should be kept in mind as a rare cause of hepatosplenomegaly and the patient should be referred for stem cell transplantation before neurologic or visual impairment develops.

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APA: Copy

USTA, MERVE, GEYLANI GULEC, SEDA, KARAMAN, SERAP, ERDEM, ELA, EMRAL, HICRAN, & URGANCI, NAFIYE. (2012). A CASE REPORT OF MALIGNANT INFANTILE OSTEOPETROSIS. IRANIAN JOURNAL OF PEDIATRICS, 22(3), 421-424. SID. https://sid.ir/paper/581825/en

Vancouver: Copy

USTA MERVE, GEYLANI GULEC SEDA, KARAMAN SERAP, ERDEM ELA, EMRAL HICRAN, URGANCI NAFIYE. A CASE REPORT OF MALIGNANT INFANTILE OSTEOPETROSIS. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2012;22(3):421-424. Available from: https://sid.ir/paper/581825/en

IEEE: Copy

MERVE USTA, SEDA GEYLANI GULEC, SERAP KARAMAN, ELA ERDEM, HICRAN EMRAL, and NAFIYE URGANCI, “A CASE REPORT OF MALIGNANT INFANTILE OSTEOPETROSIS,” IRANIAN JOURNAL OF PEDIATRICS, vol. 22, no. 3, pp. 421–424, 2012, [Online]. Available: https://sid.ir/paper/581825/en

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