OXIDATIVE STRESS IN PSEUDOEXFOLIATION SYNDROME

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SORKHABI RANA; GHORBANIHAGHJO AMIR; AHOOR MOHAMADHOSEIN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF CURRENT OPHTHALMOLOGY Year:2011 | Volume:23 | Issue:3 Page(s): 27-32

Download Full-Text

View:

260

Download:

Cites:

Information Journal Paper

Title

OXIDATIVE STRESS IN PSEUDOEXFOLIATION SYNDROME

Author(s)

SORKHABI RANA | GHORBANIHAGHJO AMIR | AHOOR MOHAMADHOSEIN | Issue Writer Certificate

Keywords

8-HYDROXY-2’-DEOXYGUANOSINE

AQUEOUS HUMOR

TOTAL ANTIOXIDANT STATUS

PSEUDOEXFOLIATION SYNDROME

Abstract

Purpose: The objective of this study was to investigate the TOTAL ANTIOXIDANT STATUS (TAS) and DNA damage markers of serum and AQUEOUS HUMOR in patients with pseudoexfoliation (PEX) syndrome.Methods: Twenty-seven cataract patients with PEX and twenty-seven without PEX syndrome were included in the study and groups were matched for age and gender. Patients had no elevated intraocular pressure (IOP) or glaucoma. AQUEOUS HUMOR and serum samples were taken at the time of surgery and TAS and 8-HYDROXY-2’-DEOXYGUANOSINE (8OHdG) levels of all samples were determined by spectrophotometric and enzyme-linked immunosorbent assay (ELISA) methods, respectively.Results: Mean 8OHdG concentration in the PEX aqueous (3.34±1.93 ng/ml) and serum (17.63±6.78 ng/ml) samples were significantly higher than that measured in the control aqueous (1.98±0.70 ng/ml) and serum (13.63±3.54 ng/ml) samples, respectively (P=0.002, P=0.010). TAS of serum (0.60±0.15 vs.0.70±0.14 mmol/lit, P=0.022) and AQUEOUS HUMOR (0.33±0.13 vs. 0.34±0.15 mmol/lit, P=0.003) in PEX patients were lower than that of the control group.Conclusion: The increased 8OHdG levels in the AQUEOUS HUMOR and serum of PEX patients suggests that oxidative DNA damage may play a role in the pathophysiology of PEX.

Cites

No record.

References

No record.

Cite

APA: Copy

SORKHABI, RANA, GHORBANIHAGHJO, AMIR, & AHOOR, MOHAMADHOSEIN. (2011). OXIDATIVE STRESS IN PSEUDOEXFOLIATION SYNDROME. JOURNAL OF CURRENT OPHTHALMOLOGY, 23(3), 27-32. SID. https://sid.ir/paper/582603/en

Vancouver: Copy

SORKHABI RANA, GHORBANIHAGHJO AMIR, AHOOR MOHAMADHOSEIN. OXIDATIVE STRESS IN PSEUDOEXFOLIATION SYNDROME. JOURNAL OF CURRENT OPHTHALMOLOGY[Internet]. 2011;23(3):27-32. Available from: https://sid.ir/paper/582603/en

IEEE: Copy

RANA SORKHABI, AMIR GHORBANIHAGHJO, and MOHAMADHOSEIN AHOOR, “OXIDATIVE STRESS IN PSEUDOEXFOLIATION SYNDROME,” JOURNAL OF CURRENT OPHTHALMOLOGY, vol. 23, no. 3, pp. 27–32, 2011, [Online]. Available: https://sid.ir/paper/582603/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops