SYNERGISTIC EFFECTS OF VITAMIN A AND EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIELD (50HZ) ON LIMB BUD DEVELOPMENT IN BALB/C MOUSE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

BAHARARA J.; ASHRAF A.R.; MADADI EMAMCHI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahrekord University of Medical Sciences Year:2010 | Volume:12 | Issue:2 Page(s): 7-14

Download Full-Text

Persian Verion

View:

901

Download:

Cites:

Information Journal Paper

Title

SYNERGISTIC EFFECTS OF VITAMIN A AND EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIELD (50HZ) ON LIMB BUD DEVELOPMENT IN BALB/C MOUSE

Author(s)

BAHARARA J. | ASHRAF A.R. | MADADI EMAMCHI M. | Issue Writer Certificate

Keywords

CHONDROGENESISQ3

ELECTROMAGNETIC FIELDQ3

LIMB BUDQ3

VITAMIN A.Q3

Abstract

Background and aim: VITAMIN A.is involved in vertebrate morphogenesis, growth, cellular differentiation, and tissue homeostasis. VITAMIN A.and its metabolites are essential for adequate embryo development. ELECTROMAGNETIC FIELDs (EMFs) have been used effectively to treat some diseases, such as certain musculoskeletal and chondrogenic disorders. In the present study, we aimed to investigate the synergistic effects of EMFs and VITAMIN A.on LIMB BUD development in Balb/C mice in vivo. Methods: The Balb/C mice were used as experimental model. After mating, the pregnant mice were divided randomly into 3 groups as control, sham and experimental groups. Control and experimental groups received a single dose injection of VITAMIN A.(15000IU/Kg) on 10.5th gestational day, interaperitonealy. In addition, animals in experimental group were exposed to EMFs (50 Hz /100 gauss, for 4 h during three days). The animals were killed on the 15.5th day of gestation and were submitted to caesarian section. The obtained fetuses were examined externally with an analyzed under a stereoscopic microscope and were photographed. Data were analyzed statistically by t-test and ANOVA and Ktuskal- Wallis. Results: Morphological and histological examinations showed significant changes in LIMB BUDs as compared with sham exposed and control groups. In both fore and hind LIMB BUDs significant decrease obtained in proximo-distal (P-D) and anterior posterior (A-P) axes (P<0.05). Chondrocytes counts revealed a significant delay in the development of chondrocytes in experimental groups as compared with sham exposed and control groups (P<0.05). Conclusion: Synergistic effects of VITAMIN A.and extremely low frequency ELECTROMAGNETIC FIELD (50Hz) cause delay in development.

Cites

No record.

References

No record.

Cite

APA: Copy

BAHARARA, J., ASHRAF, A.R., & MADADI EMAMCHI, M.. (2010). SYNERGISTIC EFFECTS OF VITAMIN A AND EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIELD (50HZ) ON LIMB BUD DEVELOPMENT IN BALB/C MOUSE. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 12(2), 7-14. SID. https://sid.ir/paper/58308/en

Vancouver: Copy

BAHARARA J., ASHRAF A.R., MADADI EMAMCHI M.. SYNERGISTIC EFFECTS OF VITAMIN A AND EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIELD (50HZ) ON LIMB BUD DEVELOPMENT IN BALB/C MOUSE. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2010;12(2):7-14. Available from: https://sid.ir/paper/58308/en

IEEE: Copy

J. BAHARARA, A.R. ASHRAF, and M. MADADI EMAMCHI, “SYNERGISTIC EFFECTS OF VITAMIN A AND EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIELD (50HZ) ON LIMB BUD DEVELOPMENT IN BALB/C MOUSE,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 12, no. 2, pp. 7–14, 2010, [Online]. Available: https://sid.ir/paper/58308/en

Related Journal Papers