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Information Journal Paper

Title

THE EFFECT OF RESISTANCE TRAINING ON PLASMA AND SKELETAL MUSCLES SPHINGOSINE-1-PHOSPHATE LEVELS OF MALE WISTAR RAT

Pages

  1-10

Keywords

SPHINGOSINE-1-PHOSPHATE (S1P)Q2

Abstract

 Background and aims: Sphingosine 1-phosphate (S1P) is a bioactive platelet-derived sphingolipid that is involved in regulation of proliferation, differentiation, hypertrophy and antiapoptosis of cells and activation of satellite cells. The purpose of present study was to examine the effect of resistance training on S1P levels of PLASMA and skeletal muscles in male Wistar rats.Methods: Twenty four 8-week-old male Wistar rats were used in this study. The initial body weight of rats was 190 to 250 gr. All animals were maintained in pairs in an environmentally controlled room at 22oC, 12: 12-h photoperiod cycle and allowed normal cage activity. The animals were fed standard rat chow and water ad libitum. After a week of acclimation to the animal facility, the rats were assigned randomly to a control (N=12) or training (N=12) group. Resistance training was done using a 1 meter height ladder with 2 cm grid with an 85 degree incline, and weights attached to rat's tails. The content of sphingosine-1- phosphate (S1P) present in the chloroform layer was determined by means of high performance liquid chromatography (HPLC).Results: Resistance exercise training increased the total content of S1P in FHL (fast-twitch) (P=0.003) and soleus (slow-twitch) (P=0.008) muscles and PLASMA (P=0.001) in comparison with control group.Conclusion: It is concluded that resistance exercise training strongly affects the S1P content in fast and SLOW TWITCH muscles and PLASMA.

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    APA: Copy

    BANITALEBI, E., GHARAKHANLOU, R., GHATREH SAMANI, K., MOHAMMAD AMOLI, M., & TEIMORI, H.. (2012). THE EFFECT OF RESISTANCE TRAINING ON PLASMA AND SKELETAL MUSCLES SPHINGOSINE-1-PHOSPHATE LEVELS OF MALE WISTAR RAT. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 14(1), 1-10. SID. https://sid.ir/paper/58361/en

    Vancouver: Copy

    BANITALEBI E., GHARAKHANLOU R., GHATREH SAMANI K., MOHAMMAD AMOLI M., TEIMORI H.. THE EFFECT OF RESISTANCE TRAINING ON PLASMA AND SKELETAL MUSCLES SPHINGOSINE-1-PHOSPHATE LEVELS OF MALE WISTAR RAT. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;14(1):1-10. Available from: https://sid.ir/paper/58361/en

    IEEE: Copy

    E. BANITALEBI, R. GHARAKHANLOU, K. GHATREH SAMANI, M. MOHAMMAD AMOLI, and H. TEIMORI, “THE EFFECT OF RESISTANCE TRAINING ON PLASMA AND SKELETAL MUSCLES SPHINGOSINE-1-PHOSPHATE LEVELS OF MALE WISTAR RAT,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 14, no. 1, pp. 1–10, 2012, [Online]. Available: https://sid.ir/paper/58361/en

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