THE HEALING POWER OF ALOE VERA MUCILAGE: INDUCTION OF INSULIN-LIKE GROWTH FACTOR GENE EXPRESSION AND REGENERATION TISSUE IN MOUSE DAMAGED SKIN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NAJAFI N.; ARABI M.; JAFARZADEH H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahrekord University of Medical Sciences Year:2014 | Volume:16 | Issue:2 Page(s): 1-9

Download Full-Text

Persian Verion

View:

983

Download:

Cites:

Information Journal Paper

Title

THE HEALING POWER OF ALOE VERA MUCILAGE: INDUCTION OF INSULIN-LIKE GROWTH FACTOR GENE EXPRESSION AND REGENERATION TISSUE IN MOUSE DAMAGED SKIN

Author(s)

NAJAFI N. | ARABI M. | JAFARZADEH H. | Issue Writer Certificate

Keywords

ALOE VERAQ2

MUCILAGEQ2

WOUND HEALINGQ2

GENE EXPRESSIONQ2

INSULIN-LIKE GROWTH FACTORQ2

Abstract

Background and aims: ALOE VERA (AV) (Aloe barbadensis Miller) is a tropical plant which has been introduced for healing of burns and wounds. The current study was aimed to assess the effects AV MUCILAGE on WOUND HEALING process in mouse damaged skin.Methods: In this experimental study, 30 balb/c male mice with weight range 22±2 gr were divided into 5 groups without wound (negative control), wound treated with physiological serum for a period of 8 days (sham-operated), wound treated with physiological serum for a period of 16 days, wound treated with Aloe MUCILAGE for a period of 8 days (experimental) and wound treated with Aloe MUCILAGE for a period of 16 days (experimental). Two equal full-thickness wounds of 10±2 mm were made with taking full-thickness skin. On 8th and 16th post wounding day, sampling was performed to assess IGF (insulin-like growth factor) receptor GENE EXPRESSION by RT-PCR and histological changes. Data were analyzed using one way ANOVA and (Tukey’s hsd post hoc) statically tests.Results: AV MUCILAGE treatments significantly increased IGF GENE EXPRESSIONs compared to sham-operated group during 8 and 16 days following wounding (P<0.05). AV treatments elevated re-epithelization production with increased mitotic activity in fibroblasts, fibrocytes, collagen fibers and angiogenesis in damaged areas.Conclusion: AV MUCILAGE may use as a strength wound healer to heal skin damages in many kinds of animal skin damages.

Cites

No record.

References

No record.

Cite

APA: Copy

NAJAFI, N., ARABI, M., & JAFARZADEH, H.. (2014). THE HEALING POWER OF ALOE VERA MUCILAGE: INDUCTION OF INSULIN-LIKE GROWTH FACTOR GENE EXPRESSION AND REGENERATION TISSUE IN MOUSE DAMAGED SKIN. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 16(2), 1-9. SID. https://sid.ir/paper/58379/en

Vancouver: Copy

NAJAFI N., ARABI M., JAFARZADEH H.. THE HEALING POWER OF ALOE VERA MUCILAGE: INDUCTION OF INSULIN-LIKE GROWTH FACTOR GENE EXPRESSION AND REGENERATION TISSUE IN MOUSE DAMAGED SKIN. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;16(2):1-9. Available from: https://sid.ir/paper/58379/en

IEEE: Copy

N. NAJAFI, M. ARABI, and H. JAFARZADEH, “THE HEALING POWER OF ALOE VERA MUCILAGE: INDUCTION OF INSULIN-LIKE GROWTH FACTOR GENE EXPRESSION AND REGENERATION TISSUE IN MOUSE DAMAGED SKIN,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 2, pp. 1–9, 2014, [Online]. Available: https://sid.ir/paper/58379/en

Related Journal Papers