THE CORRELATION BETWEEN HEPATITIS E SEROPOSITIVENESS AND INTRAVENOUS DRUG USING IN THE DRUG USERS WHO REFERRED TO THE DRUG TREATMENT CENTERS IN AHVAZ, 2005-2006

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ALAVI S.M.; AHMADI F.; NIKKHOUI A.; GHASEMIRAD M.R.

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Journal: Journal of Shahrekord University of Medical Sciences Year:2007 | Volume:9 | Issue:3 Page(s): 15-20

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Title

THE CORRELATION BETWEEN HEPATITIS E SEROPOSITIVENESS AND INTRAVENOUS DRUG USING IN THE DRUG USERS WHO REFERRED TO THE DRUG TREATMENT CENTERS IN AHVAZ, 2005-2006

Author(s)

ALAVI S.M. | AHMADI F. | NIKKHOUI A. | GHASEMIRAD M.R. | Issue Writer Certificate

Keywords

BLOOD TRANSFUSIONQ3

DRUG USINGQ2

HEPATITIS EQ3

INTERAVENOUSQ2

Abstract

Background and aim: HEPATITIS E virus (HEV) infection is endemic in Iran and some cases of fulminant hepatit with high mortality rate caused by this virus have been reported in patients with chronic HEPATITIS E and in pregnant women. Although HEV is mainly transmitted via fecal-oral route, but recently there have been some reports indicating transition of this virus via transfusion. Therefore, this study was aimed to investigate the association of HEPATITIS E seropositiveness and intravenous DRUG USING in the drug users.Method: This is an analytical-descriptive study which was conducted in a drug treatment center in Ahvaz from 2005 to 2006. A total of 114 intravenous drug users (IVDUs) and 114 inhaling addicts (IADs) were subjected to full physical examination. Subsequently a questionnaire including individual characteristics and related variations was filled in and also a blood sample was obtained. Using ELISA method, the samples were tested for anti-HEV antibody. Data were analyzed using Chi square, t and odds ration (OR) tests.Results: The mean age of the two groups, IVDUs and IADs, were 33.24±8.04 and 31.2±7.59 years respectively, with no significant difference (P>0.05). The mean of duration of addiction in IVDUs and IADs groups was 11.58±6.92 and 9.95±6.42 years, respectively (P>0.05). Anti-HEV antibody was detected in 22.8% of IVDUs and 7.9% of IADs (P<0.01, OR=3.44). There was no significant relationship between previous imprisonment and anti-HEV antibody positiveness in the drug addicts studied (P>0.05, OR=1.15).Conclusion: As it was shown in this study, HEV is probably transmitted via BLOOD TRANSFUSION and thus screening of blood donors for anti-HEV antibody may block this route of infection.

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APA: Copy

ALAVI, S.M., AHMADI, F., NIKKHOUI, A., & GHASEMIRAD, M.R.. (2007). THE CORRELATION BETWEEN HEPATITIS E SEROPOSITIVENESS AND INTRAVENOUS DRUG USING IN THE DRUG USERS WHO REFERRED TO THE DRUG TREATMENT CENTERS IN AHVAZ, 2005-2006. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 9(3), 15-20. SID. https://sid.ir/paper/58653/en

Vancouver: Copy

ALAVI S.M., AHMADI F., NIKKHOUI A., GHASEMIRAD M.R.. THE CORRELATION BETWEEN HEPATITIS E SEROPOSITIVENESS AND INTRAVENOUS DRUG USING IN THE DRUG USERS WHO REFERRED TO THE DRUG TREATMENT CENTERS IN AHVAZ, 2005-2006. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2007;9(3):15-20. Available from: https://sid.ir/paper/58653/en

IEEE: Copy

S.M. ALAVI, F. AHMADI, A. NIKKHOUI, and M.R. GHASEMIRAD, “THE CORRELATION BETWEEN HEPATITIS E SEROPOSITIVENESS AND INTRAVENOUS DRUG USING IN THE DRUG USERS WHO REFERRED TO THE DRUG TREATMENT CENTERS IN AHVAZ, 2005-2006,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 9, no. 3, pp. 15–20, 2007, [Online]. Available: https://sid.ir/paper/58653/en

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