Optimization the synthesis of functionalized silica nanoparticles by temperature magnetic stirring method and study the effect of various parameters by an irregular factorial design

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

VARSHOSAZ J.; Golestaneh d.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahrekord University of Medical Sciences Year:2018 | Volume:20 | Issue:3 Page(s): 108-120

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

490

Download:

Cites:

Information Journal Paper

Title

Optimization the synthesis of functionalized silica nanoparticles by temperature magnetic stirring method and study the effect of various parameters by an irregular factorial design

Author(s)

VARSHOSAZ J. | Golestaneh d. | Issue Writer Certificate

Keywords

Silicon dioxideQ1

NanoparticlesQ1

Drug delivery systemsQ1

Abstract

Background and aims: Silica Nanoparticles are biodegradable novel Drug delivery systems and their biodegradation in vivo is affected by their particle size and their surface properties and for this reasons they are suitable for drug conjugation and biomedical applications. The aim of the present study were optimization of the particle size and zeta potential, investigation of the effect of various parameters and finally obtain equations for the estimation of the particle size and zeta potential in synthesis of functionalized silica Nanoparticles. Methods: The NH2 functionalized silica Nanoparticles were synthesized by simultaneous hydrolysis of tetraethyl orthosilicate and )3-aminopropyl( triethoxysilan in the presence of ammonium hydroxide and ethanol by temperature magnetic stirring method and the properties of particle size and zeta potential were studied. The effective parameters were determined by an irregular factorial design. The synthesis of the Nanoparticles was confirmed by Fourier transform infrared spectroscopy and transmission electron microscopy. Results: The amount of ammonium hydroxide and ethanol had a significant effect on the size and zeta potential of Nanoparticles (P<0. 05). Reduction of ammonium hydroxide and ethanol increase dicreases significantly the particle size. Also, by increasing ammonium hydroxide and decreasing ethanol, the absolute magnitude of zeta potential increased significantly. Conclusion: Irregular factorial design is a suitable method for optimization of synthesis of modified silica Nanoparticles.

Cites

No record.

References

No record.

Cite

APA: Copy

VARSHOSAZ, J., & Golestaneh, d.. (2018). Optimization the synthesis of functionalized silica nanoparticles by temperature magnetic stirring method and study the effect of various parameters by an irregular factorial design. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 20(3 ), 108-120. SID. https://sid.ir/paper/58852/en

Vancouver: Copy

VARSHOSAZ J., Golestaneh d.. Optimization the synthesis of functionalized silica nanoparticles by temperature magnetic stirring method and study the effect of various parameters by an irregular factorial design. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;20(3 ):108-120. Available from: https://sid.ir/paper/58852/en

IEEE: Copy

J. VARSHOSAZ, and d. Golestaneh, “Optimization the synthesis of functionalized silica nanoparticles by temperature magnetic stirring method and study the effect of various parameters by an irregular factorial design,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 20, no. 3 , pp. 108–120, 2018, [Online]. Available: https://sid.ir/paper/58852/en

Related Journal Papers