EFFECTS OF CAFFEINE INJECTION IN PARADOXICAL SLEEP WINDOW ON MEMORY IN RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NABAEI E.; MOTAMEDI F.; SHARIATZADEH S.M.A.; NABAEI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download Full-Text

Persian Verion

View:

1,104

Download:

Cites:

Information Journal Paper

Title

EFFECTS OF CAFFEINE INJECTION IN PARADOXICAL SLEEP WINDOW ON MEMORY IN RAT

Author(s)

NABAEI E. | MOTAMEDI F. | SHARIATZADEH S.M.A. | NABAEI M. | Issue Writer Certificate

Keywords

ADENOSINEQ3

CAFFEINEQ2

MEMORYQ2

PARADOXICAL SLEEP WINDOWSQ2

REM SLEEP DEPRIVATIONQ2

RATQ2

Abstract

Background and aim: Some investigators believe that the amount of REM sleep is increased after learning of some tasks, and learning processing and MEMORY consolidation occur during some of these periods. These specific periods are called PARADOXICAL SLEEP WINDOWS (PSW). The neurochemical nature of PSW and its active neurotransmitter are unknown.Methods: NMRI RATs were trained in a two-way shuttle avoidance task (100 trials per one session) and MEMORY retention was tested one week later. Those animals that reached to 70% learning criterion were divided into 8 groups. In drug section, the animals of each group were administrated saline, CAFFEINE (25mg/kg), ADENOSINE (7mg/kg), ADENOSINE (50mg/kg), physostigmine (0.1mg/kg) or Scopolamine (5mg/kg i.p.), after learning. In drug-deprivation section, the first group was deprived from REM sleep for 1-4hr after learning with platform technique. Animals in second group were administrated CAFFEINE (25mg/kg) in addition to REM SLEEP DEPRIVATION for 1-4 hr after learning.Results: Injection of CAFFEINE caused a significant increase in MEMORY (P<0.05). Deprived animals showed a significant MEMORY deficit (P<0.05) and CAFFEINE attenuated MEMORY impairment which was induced by paradoxical sleep deprivation. Other drugs had no significant effect on MEMORY.Conclusion: CAFFEINE can enhance MEMORY and attenuate paradoxical sleep deprivation-induced MEMORY impairment. Effects of CAFFEINE on MEMORY involve systems other than cholinergic and ADENOSINE systems. MEMORY processing which occurs in PSW cannot be attributed to one neurotransmitter system.

Cites

No record.

References

No record.

Cite

APA: Copy

NABAEI, E., MOTAMEDI, F., SHARIATZADEH, S.M.A., & NABAEI, M.. (2011). EFFECTS OF CAFFEINE INJECTION IN PARADOXICAL SLEEP WINDOW ON MEMORY IN RAT. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 13(1), 48-54. SID. https://sid.ir/paper/58973/en

Vancouver: Copy

NABAEI E., MOTAMEDI F., SHARIATZADEH S.M.A., NABAEI M.. EFFECTS OF CAFFEINE INJECTION IN PARADOXICAL SLEEP WINDOW ON MEMORY IN RAT. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2011;13(1):48-54. Available from: https://sid.ir/paper/58973/en

IEEE: Copy

E. NABAEI, F. MOTAMEDI, S.M.A. SHARIATZADEH, and M. NABAEI, “EFFECTS OF CAFFEINE INJECTION IN PARADOXICAL SLEEP WINDOW ON MEMORY IN RAT,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 13, no. 1, pp. 48–54, 2011, [Online]. Available: https://sid.ir/paper/58973/en

Related Journal Papers