THE RELATIONSHIP OF ALUMINIUM AND SILVER TO NEURAL TUBE DEFECTS; A CASE CONTROL

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RAMIREZ ALTAMIRANO MARIA DE JESUS; FENTON NAVARRO PATRICIA; SIVET CHINAS ELVIRA; HARP ITURRIBARRIA FLOR DE MARIA; MARTINEZ CRUZ RUTH; HERNANDEZ CRUZ PEDRO; CRUZ MARGARITO MARTINEZ; PEREZ CAMPOS EDUARDO

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Journal Paper

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Journal: Iranian Journal of Pediatrics Year:2012 | Volume:22 | Issue:3 Page(s): 369-374

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Title

THE RELATIONSHIP OF ALUMINIUM AND SILVER TO NEURAL TUBE DEFECTS; A CASE CONTROL

Author(s)

Keywords

ALUMINIUM

SILVER

HAIR

NEWBORNS

NEURAL TUBE DEFECTS

Abstract

Objective: The purpose of this study was to identify the relationship of neurotoxic inorganic elements in the HAIR of patients with the diagnosis of NEURAL TUBE DEFECTS. Our initial hypothesis was that neurotoxic inorganic elements were associated with NEURAL TUBE DEFECTS.Methods: Twenty-three samples of HAIR from NEWBORNS were obtained from the General Hospital, “Aurelio Valdivieso” in the city of Oaxaca, Mexico. The study group included 8 newborn infants with neural tube pathology. The control group was composed of 15 NEWBORNS without this pathology. The presence of inorganic elements in the HAIR samples was determined by inductively-coupled plasma spectroscopy (spectroscopic emission of the plasma).Findings: The population of NEWBORNS with NEURAL TUBE DEFECTS showed significantly higher values of the following elements than the control group: ALUMINIUM, NEURAL TUBE DEFECTS 152.77±51.06 mg/g, control group 76.24±27.89 mg/g; SILVER, NEURAL TUBE DEFECTS 1.45±0.76, control group 0.25±0.53 mg/g; Potassium, NEURAL TUBE DEFECTS 553.87±77.91 mg/g, control group 341.13±205.90 mg/g. Association was found at 75 percentile between ALUMINIUM plus SILVER, ALUMINIUM plus potassium, SILVER plus potassium, and potassium plus sodium.Conclusion: In the HAIR of NEWBORNS with NEURAL TUBE DEFECTS, the following metals were increased: ALUMINIUM, SILVER. Given the neurotoxicity of the same, and association of NEURAL TUBE DEFECTS with aluminum and SILVER, one may infer that they may be participating as factors in the development of NEURAL TUBE DEFECTS.

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APA: Copy

RAMIREZ ALTAMIRANO, MARIA DE JESUS, FENTON NAVARRO, PATRICIA, SIVET CHINAS, ELVIRA, HARP ITURRIBARRIA, FLOR DE MARIA, MARTINEZ CRUZ, RUTH, HERNANDEZ CRUZ, PEDRO, CRUZ, MARGARITO MARTINEZ, & PEREZ CAMPOS, EDUARDO. (2012). THE RELATIONSHIP OF ALUMINIUM AND SILVER TO NEURAL TUBE DEFECTS; A CASE CONTROL. IRANIAN JOURNAL OF PEDIATRICS, 22(3), 369-374. SID. https://sid.ir/paper/590435/en

Vancouver: Copy

RAMIREZ ALTAMIRANO MARIA DE JESUS, FENTON NAVARRO PATRICIA, SIVET CHINAS ELVIRA, HARP ITURRIBARRIA FLOR DE MARIA, MARTINEZ CRUZ RUTH, HERNANDEZ CRUZ PEDRO, CRUZ MARGARITO MARTINEZ, PEREZ CAMPOS EDUARDO. THE RELATIONSHIP OF ALUMINIUM AND SILVER TO NEURAL TUBE DEFECTS; A CASE CONTROL. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2012;22(3):369-374. Available from: https://sid.ir/paper/590435/en

IEEE: Copy

MARIA DE JESUS RAMIREZ ALTAMIRANO, PATRICIA FENTON NAVARRO, ELVIRA SIVET CHINAS, FLOR DE MARIA HARP ITURRIBARRIA, RUTH MARTINEZ CRUZ, PEDRO HERNANDEZ CRUZ, MARGARITO MARTINEZ CRUZ, and EDUARDO PEREZ CAMPOS, “THE RELATIONSHIP OF ALUMINIUM AND SILVER TO NEURAL TUBE DEFECTS; A CASE CONTROL,” IRANIAN JOURNAL OF PEDIATRICS, vol. 22, no. 3, pp. 369–374, 2012, [Online]. Available: https://sid.ir/paper/590435/en

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