THE EFFECT OF ORDER OF INJECTION OF PROPOFOL AND REMIFENTANIL ON HEMODYNAMIC CHANGES DURING INDUCTION OF ANESTHESIA

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RAHIMI PANAHI J.; MAHMOUDPOUR ATA; NEGARGAR S.; AZAR FARIN R.

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Journal: JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS) Year:2005 | Volume:5 | Issue:16 Page(s): 142-145

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Title

THE EFFECT OF ORDER OF INJECTION OF PROPOFOL AND REMIFENTANIL ON HEMODYNAMIC CHANGES DURING INDUCTION OF ANESTHESIA

Author(s)

RAHIMI PANAHI J. | MAHMOUDPOUR ATA | NEGARGAR S. | AZAR FARIN R. | Issue Writer Certificate

Keywords

PROPOFOLQ3

REMIFENTANILQ3

INDUCTIONQ4

TRACHEAL INTUBATIONQ3

Abstract

Background & Objectives: One of the most common ways in intubation without muscle relaxant is using PROPOFOL and REMIFENTANIL. The common practice is injection of REMIFENTANIL and then PROPOFOL This occasionally produces severe hemodynamic changes. The aim of this study is to inject PROPOFOL followed by REMIFENTANIL for evaluating the effect of the order of injection on decreasing these complications. Methods: 40 patients with American Society of Anesthesia (ASA) class I-II, who underwent minor elective surgery with airway mallampati class I-II entered the study. Patients were randomized into 2 groups each with 20 patients. The first group received 2.5mg/kg PROPOFOL followed by 1.5 µ g/mg REMIFENTANIL while the second group received 1.5 µ g/mg REMIFENTANIL followed by 2.5 mg/kg PROPOFOL Laryngoscopy and hemodynamic changes were compared in two groups. Results: There was no difference between two groups in laryngoscopy attempts (P=0.1 45) but the frequency of easy laryngoscopy in the first group (85%) was more than the second group (60%) (P=0.031). Systolic blood pressure changes after laryngoscopy in the first group (20±7.7 mmHg) was less than the second group (28±6.7 mmHg) (P=0.001). There was no statistical significant difference between two groups in diastolic blood pressure and heart rate changes (P=0.88, P=0.86 respectively). Conclusion: Administrations of propotol before REMIFENTANIL during anesthesia INDUCTION produces acceptable hemodynamic changes in patients.

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APA: Copy

RAHIMI PANAHI, J., MAHMOUDPOUR, ATA, NEGARGAR, S., & AZAR FARIN, R.. (2005). THE EFFECT OF ORDER OF INJECTION OF PROPOFOL AND REMIFENTANIL ON HEMODYNAMIC CHANGES DURING INDUCTION OF ANESTHESIA. JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS), 5(16), 142-145. SID. https://sid.ir/paper/59639/en

Vancouver: Copy

RAHIMI PANAHI J., MAHMOUDPOUR ATA, NEGARGAR S., AZAR FARIN R.. THE EFFECT OF ORDER OF INJECTION OF PROPOFOL AND REMIFENTANIL ON HEMODYNAMIC CHANGES DURING INDUCTION OF ANESTHESIA. JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS)[Internet]. 2005;5(16):142-145. Available from: https://sid.ir/paper/59639/en

IEEE: Copy

J. RAHIMI PANAHI, ATA MAHMOUDPOUR, S. NEGARGAR, and R. AZAR FARIN, “THE EFFECT OF ORDER OF INJECTION OF PROPOFOL AND REMIFENTANIL ON HEMODYNAMIC CHANGES DURING INDUCTION OF ANESTHESIA,” JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS), vol. 5, no. 16, pp. 142–145, 2005, [Online]. Available: https://sid.ir/paper/59639/en

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