THE EFFECT OF TRANEXAMIC ACID ON REDUCTION OF SECONDARY HEMORRHAGE IN THE TRAUMATIC HYPHEMA

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MASOUMI R.; MASOUMI N.; FOULADI N.; SAMIEE E.

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Paper Information

Journal: Journal of Ardabil University of Medical Sciences Year:2011 | Volume:11 | Issue:3 (41) Page(s): 259-268

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Title

THE EFFECT OF TRANEXAMIC ACID ON REDUCTION OF SECONDARY HEMORRHAGE IN THE TRAUMATIC HYPHEMA

Author(s)

MASOUMI R. | MASOUMI N. | FOULADI N. | SAMIEE E. | Issue Writer Certificate

Keywords

HYPHEMAQ3

BLUNT TRAUMAQ2

TRANEXAMIC ACIDQ2

SECONDARY HEMORRHAGEQ3

Abstract

Background & Objectives: HYPHEMA which commonly caused by the BLUNT TRAUMA, is defined as blood accumulation in the anterior chamber of the eye. It is associated with several complications from which SECONDARY HEMORRHAGE is more important. This study was aimed to determine TRANEXAMIC ACID effect on reduction of the SECONDARY HEMORRHAGE in traumatic HYPHEMA.Methods: This study was a randomized controlled trial in 54 patients with traumatic HYPHEMA referred to ophthalmology clinic of Alavi Hospital in Ardabil during 2006-2008. The patients were divided into two groups. Half of the patients received TRANEXAMIC ACID and the rest used placebo. After examination of the eyes, the data were analyzed by using Chi-square and Student-t tests.Results: In this study 79.6% of patients were men and the rest were women. They had 19.8±9.44 years old as mean. The vision for 33.3% of the individuals showed light perception ,29.6% hand motion and 35.2% of them indicated finger count. 1.9% of patients had grade I, 11.1%grade II, 38.9% grade III and 48.1% grade IV HYPHEMA. The patients who received TRANEXAMIC ACID did not show SECONDARY HEMORRHAGE but five untreated individuals were undergone bleeding.Conclousion: TRANEXAMIC ACID reduced SECONDARY HEMORRHAGE in patients with BLUNT TRAUMArelated HYPHEMA. We suggest further studies of relationship between intra-ocular pressure and SECONDARY HEMORRHAGE rate.

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APA: Copy

MASOUMI, R., MASOUMI, N., FOULADI, N., & SAMIEE, E.. (2011). THE EFFECT OF TRANEXAMIC ACID ON REDUCTION OF SECONDARY HEMORRHAGE IN THE TRAUMATIC HYPHEMA. JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS), 11(3 (41)), 259-268. SID. https://sid.ir/paper/59670/en

Vancouver: Copy

MASOUMI R., MASOUMI N., FOULADI N., SAMIEE E.. THE EFFECT OF TRANEXAMIC ACID ON REDUCTION OF SECONDARY HEMORRHAGE IN THE TRAUMATIC HYPHEMA. JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS)[Internet]. 2011;11(3 (41)):259-268. Available from: https://sid.ir/paper/59670/en

IEEE: Copy

R. MASOUMI, N. MASOUMI, N. FOULADI, and E. SAMIEE, “THE EFFECT OF TRANEXAMIC ACID ON REDUCTION OF SECONDARY HEMORRHAGE IN THE TRAUMATIC HYPHEMA,” JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS), vol. 11, no. 3 (41), pp. 259–268, 2011, [Online]. Available: https://sid.ir/paper/59670/en

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