THERAPEUTIC EFFICACY OF TOPICAL FLUOROURACIL AND CRYOTHERAPY IN THE TREATMENT OF PLANTAR WARTS

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SAYAD REZAEI I.; ROSTAMI MOGHADAM M.

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Paper Information

Journal: JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS) Year:2008 | Volume:8 | Issue:3 (29) Page(s): 270-273

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Title

THERAPEUTIC EFFICACY OF TOPICAL FLUOROURACIL AND CRYOTHERAPY IN THE TREATMENT OF PLANTAR WARTS

Author(s)

SAYAD REZAEI I. | ROSTAMI MOGHADAM M. | Issue Writer Certificate

Keywords

PLANTAR WARTSQ3

5- FLUOROURACILQ3

CRYOTHERAPYQ2

Abstract

Background & objectives: Warts are common dermatological disorder which is difficult to treat and usually relapse. In this study the efficacy of topical %5 5- FLUOROURACIL was compared with conventional CRYOTHERAPY in treatment of PLANTAR WARTS.Methods: In a clinical trial study, 50 patients clinically diagnosed as warts were divided in to two groups. 25 patients were treated with topical 5% 5- FLUOROURACIL while the other 25 were treated with CRYOTHERAPY. After treatment, patients were followed for 6 months from the viewpoints of treatment complication, efficacy and relapse rate.Results: It was observed that treating period in CRYOTHERAPY was short but 5F-U therapy needed longer time. Initially in 5-FU group 52% of patient had good response, 36%moderate response and in 12% no response was observed there is no significant difference in view of sex in this group (p=51%) and in CRYOTHERAPY group 60% of patients had good response, 28% moderate response and in 12% no response was observed likewise there was no significant difference in terms of gender (p=0.08). In response to therapy there was no difference between two groups (p=0.09%) after 6 months follow up relapse rate was 18% in CRYOTHERAPY patients and only 8%in 5-FU group which wasn't statistically meaningful and no difference was observed between two groups (p=0.27).Conclusion: The results indicated that course of treatment was shorter in CRYOTHERAPY than the topical 5- FU but the relapse rate didn’t have any difference between two groups. The only significant difference was pain in which 5- FU was painless but CRYOTHERAPY was painful.

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APA: Copy

SAYAD REZAEI, I., & ROSTAMI MOGHADAM, M.. (2008). THERAPEUTIC EFFICACY OF TOPICAL FLUOROURACIL AND CRYOTHERAPY IN THE TREATMENT OF PLANTAR WARTS. JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS), 8(3 (29)), 270-273. SID. https://sid.ir/paper/59852/en

Vancouver: Copy

SAYAD REZAEI I., ROSTAMI MOGHADAM M.. THERAPEUTIC EFFICACY OF TOPICAL FLUOROURACIL AND CRYOTHERAPY IN THE TREATMENT OF PLANTAR WARTS. JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS)[Internet]. 2008;8(3 (29)):270-273. Available from: https://sid.ir/paper/59852/en

IEEE: Copy

I. SAYAD REZAEI, and M. ROSTAMI MOGHADAM, “THERAPEUTIC EFFICACY OF TOPICAL FLUOROURACIL AND CRYOTHERAPY IN THE TREATMENT OF PLANTAR WARTS,” JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS), vol. 8, no. 3 (29), pp. 270–273, 2008, [Online]. Available: https://sid.ir/paper/59852/en

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