RELATION OF RESISTIN LEVELS WITH C-REACTVE PROTEIN, HOMOCYSTEINE AND URIC ACID IN SMOKERS AND NON-SMOKERS

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ESBAH ONUR; GURSOY GUL; KIRNAP NAZLI GULSOY; CETINER HACER; DEMIRBAS BERRIN; ACAR YASAR; BAYRAM MURAT

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2011 | Volume:16 | Issue:10 Page(s): 1273-1279

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Title

RELATION OF RESISTIN LEVELS WITH C-REACTVE PROTEIN, HOMOCYSTEINE AND URIC ACID IN SMOKERS AND NON-SMOKERS

Author(s)

Keywords

CRP

HOMOCYSTEINE

URIC ACID

RESISTIN

SMOKING

Abstract

BACKGROUND: The association between C-reactive protein, HOMOCYSTEINE, URIC ACID levels and cardiovascular risk have been debated for decades. RESISTIN is a newly discovered adipocyte derived cytokine. SMOKING besides its effect on atherosclerosis, is shown to alter adipocytokine levels. Bearing in mind, these complex relationship of RESISTIN with SMOKING, C-reactive protein, HOMOCYSTEINE and URIC ACID, we planned to investigate the association of RESISTIN and these cardiovascular risk factors in smoker and non-smoker subjects.METHODS: We conducted a cross-sectional randomized study including 52 SMOKING and 33 non-smoking men. After making comparisons of C-reactive protein, HOMOCYSTEINE, URIC ACID and RESISTIN between the two groups, we classified the subjects according to their insulin resistance and body mass and made again the comparisons.RESULTS: RESISTIN levels were higher in smokers than in non-smokers (p<0.001) and also in insulin resistant than in non-insulin resistant smokers (p<0.05). RESISTIN levels were indifferent in non-smokers as insulin resistance was concerned and in smoker or non-smokers as body mass index was concerned. As all subjects were grouped based on homeostasis model assesment index and body mass index, neither C-reactive protein nor HOMOCYSTEINE and URIC ACID levels differred.CONCLUSIONS: We found that SMOKING may have influence on RESISTIN levels and in smokers, insulin resistance is related to RESISTIN levels, but in smoker and non-smokers body mass may not have any association with RESISTIN. RESISTIN also may not have a role in C-reactive protein, HOMOCYSTEINE and URIC ACID levels both in smokers and non-smokers.

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APA: Copy

ESBAH, ONUR, GURSOY, GUL, KIRNAP, NAZLI GULSOY, CETINER, HACER, DEMIRBAS, BERRIN, ACAR, YASAR, & BAYRAM, MURAT. (2011). RELATION OF RESISTIN LEVELS WITH C-REACTVE PROTEIN, HOMOCYSTEINE AND URIC ACID IN SMOKERS AND NON-SMOKERS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 16(10), 1273-1279. SID. https://sid.ir/paper/600969/en

Vancouver: Copy

ESBAH ONUR, GURSOY GUL, KIRNAP NAZLI GULSOY, CETINER HACER, DEMIRBAS BERRIN, ACAR YASAR, BAYRAM MURAT. RELATION OF RESISTIN LEVELS WITH C-REACTVE PROTEIN, HOMOCYSTEINE AND URIC ACID IN SMOKERS AND NON-SMOKERS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2011;16(10):1273-1279. Available from: https://sid.ir/paper/600969/en

IEEE: Copy

ONUR ESBAH, GUL GURSOY, NAZLI GULSOY KIRNAP, HACER CETINER, BERRIN DEMIRBAS, YASAR ACAR, and MURAT BAYRAM, “RELATION OF RESISTIN LEVELS WITH C-REACTVE PROTEIN, HOMOCYSTEINE AND URIC ACID IN SMOKERS AND NON-SMOKERS,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 16, no. 10, pp. 1273–1279, 2011, [Online]. Available: https://sid.ir/paper/600969/en

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