EVALUATION OF DIAGNOSTIC VALUE OF PROCALCITONIN AS A MARKER OF NEONATAL BACTERIAL INFECTIONS

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MONSEF ALIREZA; EGHBALIAN FATEMEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Iranian Journal of Pediatrics Year:2012 | Volume:22 | Issue:3 Page(s): 314-318

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Information Journal Paper

Title

EVALUATION OF DIAGNOSTIC VALUE OF PROCALCITONIN AS A MARKER OF NEONATAL BACTERIAL INFECTIONS

Author(s)

MONSEF ALIREZA | EGHBALIAN FATEMEH | Issue Writer Certificate

Keywords

INFECTION

NEWBORN

PROCALCITONIN

SENSITIVITY

SPECIFICITY

PREDICTIVE VALUE OF TESTS

Abstract

Objective: This study tried to assess SENSITIVITY, SPECIFICITY, positive and negative predictive value of PROCALCITONIN for diagnosis of neonatal bacterial INFECTIONs.Methods: This prospective cross sectional study was carried out during an 18-month period in NICU and neonatal wards of Besat Hospital in Hamedan province, Iran.39 symptomatic infants with clinical and laboratory findings in favor of bacterial INFECTION with a positive blood, CSF, and/or supra pubic urine culture entered the study; 32 NEWBORNs without any bacterial INFECTION served as control group. Quantitative PROCALCITONIN level ≥0.5 ng/ml was accepted as pathological. Finally SENSITIVITY, SPECIFICITY, positive (PPV) and negative predictive value (NPV) were calculated for PROCALCITONIN test.Findings: 20 blood cultures, 17 urine cultures and 8 CSF cultures were positive. SENSITIVITY, SPECIFICITY, PPV and NPV for PROCALCITONIN test was 76.9%, 100%, 100% and 78% respectively. Diagnostic value of PROCALCITONIN test in accordance with blood culture for mentioned items was 85%, 100%, 100% and 91.4% respectively. Its diagnostic value according to urine culture was: SENSITIVITY 70.6%, SPECIFICITY 100%, PPV 100% and NPV 86.4%, and according to CSF culture was: SENSITIVITY 75%, SPECIFICITY 100%, PPV 100% and NPV 94.1% respectively.Conclusion: The results show that the PROCALCITONIN test has high SENSITIVITY, SPECIFICITY, PPV and NPV for diagnosis of neonatal INFECTIONs.

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APA: Copy

MONSEF, ALIREZA, & EGHBALIAN, FATEMEH. (2012). EVALUATION OF DIAGNOSTIC VALUE OF PROCALCITONIN AS A MARKER OF NEONATAL BACTERIAL INFECTIONS. IRANIAN JOURNAL OF PEDIATRICS, 22(3), 314-318. SID. https://sid.ir/paper/603503/en

Vancouver: Copy

MONSEF ALIREZA, EGHBALIAN FATEMEH. EVALUATION OF DIAGNOSTIC VALUE OF PROCALCITONIN AS A MARKER OF NEONATAL BACTERIAL INFECTIONS. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2012;22(3):314-318. Available from: https://sid.ir/paper/603503/en

IEEE: Copy

ALIREZA MONSEF, and FATEMEH EGHBALIAN, “EVALUATION OF DIAGNOSTIC VALUE OF PROCALCITONIN AS A MARKER OF NEONATAL BACTERIAL INFECTIONS,” IRANIAN JOURNAL OF PEDIATRICS, vol. 22, no. 3, pp. 314–318, 2012, [Online]. Available: https://sid.ir/paper/603503/en

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