THE LONG TERM CLINICAL OUTCOME OF CENTRAL NERVOUS SYSTEM INVOLVEMENT IN BEHCET'S DISEASE, SOUTH OF IRAN

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HAKIM M.; KHOSRAVI F.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Hormozgan Medical Journal Year:2003 | Volume:7 | Issue:2 Page(s): 60-63

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Title

THE LONG TERM CLINICAL OUTCOME OF CENTRAL NERVOUS SYSTEM INVOLVEMENT IN BEHCET'S DISEASE, SOUTH OF IRAN

Author(s)

HAKIM M. | KHOSRAVI F. | Issue Writer Certificate

Keywords

BEHCET'S SYNDROMEQ3

CENTRAL NERVOUS SYSTEM DISEASESQ4

IRANQ2

Abstract

Introduction: Behcet's disease is an inflammatory disease and the aim of this study is to investigate the clinical outcome and presentations of central nervous system involvement in 500 patients with Behcet's disease in south of IRAN. Method & Material: In this cross sectional study five hundred patients with Behcet's disease diagnosed by international criteria were studied for central nervous system manifestations from 1990-2000 in Behcet's disease research clinic, Nemazi-Hospital, Shiraz, south of IRAN. The clinical diagnosis of central nervous system involvement was performed by medical team with aid of history neurological examination. Lumbar puncture and neuroimaging with CT and/or MRI. Patients suffering from headache with normal neurological examinations, lumbar puncture and imaging were excluded from the study. Information about disease course was extracted from patients' charts. The favorable outcome was defined as patients with full activity of daily living without any neurological deficit. Results: In this study of 500 patients with Behcet's disease, 15 patients (3%), had central nervous system involvement, with age ranging from 18 to 47-year old (mean age 32.5 yrs). Central nervous system involvement occurred from 2 to 20 years after onset of Behcet's disease and was followed ranging from 18 months to 12 years in this study. Spinal cord involvement was observed in 2 patients out of 15 (13.3%), both suffered from impotency. Nine of aneurysms, 4 patients (26.6%) had cerebral venous thrombosis, 3 (20%) patients had increased intracranial pressure, and 2 (13.3%) patients had papilledema in the absence of retinitis. Conclusion: Central nervous system involvement is one of the most destructive manifestations of Behcet's disease which is due to primary parenchyma involvement or secondary cerebral vessels involvement.

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APA: Copy

HAKIM, M., & KHOSRAVI, F.. (2003). THE LONG TERM CLINICAL OUTCOME OF CENTRAL NERVOUS SYSTEM INVOLVEMENT IN BEHCET'S DISEASE, SOUTH OF IRAN. HORMOZGAN MEDICAL JOURNAL, 7(2), 60-63. SID. https://sid.ir/paper/60703/en

Vancouver: Copy

HAKIM M., KHOSRAVI F.. THE LONG TERM CLINICAL OUTCOME OF CENTRAL NERVOUS SYSTEM INVOLVEMENT IN BEHCET'S DISEASE, SOUTH OF IRAN. HORMOZGAN MEDICAL JOURNAL[Internet]. 2003;7(2):60-63. Available from: https://sid.ir/paper/60703/en

IEEE: Copy

M. HAKIM, and F. KHOSRAVI, “THE LONG TERM CLINICAL OUTCOME OF CENTRAL NERVOUS SYSTEM INVOLVEMENT IN BEHCET'S DISEASE, SOUTH OF IRAN,” HORMOZGAN MEDICAL JOURNAL, vol. 7, no. 2, pp. 60–63, 2003, [Online]. Available: https://sid.ir/paper/60703/en

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