ANTIVIRAL EFFECT ASSAY OF AQUEOUS EXTRACT OF ECHIUM AMOENUM-L AGAINST HSV-1

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FARAHANI MALIHE

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Zahedan Journal of Research in Medical Sciences Year:2013 | Volume:15 | Issue:8 Page(s): 46-48

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Information Journal Paper

Title

ANTIVIRAL EFFECT ASSAY OF AQUEOUS EXTRACT OF ECHIUM AMOENUM-L AGAINST HSV-1

Author(s)

FARAHANI MALIHE | Issue Writer Certificate

Keywords

ANTIVIRAL EFFECT

ECHIUM AMOENUM L

HSV-1

Abstract

Background: Medicinal plants have been used for different diseases in past. There is an increasing need for substances with antiviral activity since the treatment of viral infections with the available antiviral drugs often leads to the problem of viral resistance. Therefore in the present study ECHIUM AMOENUM L plant with ethnomedical background was screened for antiviral activity against HSV-1 in different times.Materials and Methods: Flower part of ECHIUM AMOENUM L plant collected from Iran was extracted with different methods to obtain crude aqueous extract. This extract was screened for its cytotoxicity against Hep II cell line by CPE assay. Antiviral properties of the plant extract were determined by cytopathic effect inhibition assay.Results: ECHIUM AMOENUM L extract exhibited significant antiviral activity at non toxic concentrations to the cell line used. Findings indicated that plant extract has the most antiviral activity when it used an hour after virus inoculation.Conclusion: ECHIUM AMOENUM L plant had not toxic effect at highest concentrations to the cell lines used and showed the most antiviral activity when it used an hour after virus inoculation. Further research is needed to elucidate the active constituents of this plant which may be useful in the development of new and effective antiviral agents.

Cites

Evaluation of the Antifungal effects of various Extracts of the Aerial part and Root of Echium italicum on Candida albicans compared with two common antibiotics

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APA: Copy

FARAHANI, MALIHE. (2013). ANTIVIRAL EFFECT ASSAY OF AQUEOUS EXTRACT OF ECHIUM AMOENUM-L AGAINST HSV-1. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 15(8), 46-48. SID. https://sid.ir/paper/609382/en

Vancouver: Copy

FARAHANI MALIHE. ANTIVIRAL EFFECT ASSAY OF AQUEOUS EXTRACT OF ECHIUM AMOENUM-L AGAINST HSV-1. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2013;15(8):46-48. Available from: https://sid.ir/paper/609382/en

IEEE: Copy

MALIHE FARAHANI, “ANTIVIRAL EFFECT ASSAY OF AQUEOUS EXTRACT OF ECHIUM AMOENUM-L AGAINST HSV-1,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 15, no. 8, pp. 46–48, 2013, [Online]. Available: https://sid.ir/paper/609382/en

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