THYROID FUNCTION AND ITS RELATION TO INSULIN RESISTANCE IN WOMEN WITH GESTATIONAL DIABETES MELLITUS (GDM) COMPARED WITH HEALTHY PREGNANTWOMEN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHARIFI F.; NEZAMDIBA M.; KAMALI K.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Advances in Medical and Biomedical Research Year:2014 | Volume:22 | Issue:94 Page(s): 61-71

Download Full-Text

Persian Verion

View:

2,439

Download:

Cites:

Information Journal Paper

Title

THYROID FUNCTION AND ITS RELATION TO INSULIN RESISTANCE IN WOMEN WITH GESTATIONAL DIABETES MELLITUS (GDM) COMPARED WITH HEALTHY PREGNANTWOMEN

Author(s)

SHARIFI F. | NEZAMDIBA M. | KAMALI K. | Issue Writer Certificate

Keywords

GESTATIONAL DIABETES MELLITUSQ2

TSHQ3

ANTI-TPOQ2

INSULIN RESISTANCEQ2

SUBCLINICAL HYPOTHYROIDISMQ2

Abstract

Background and Objective: Gestational diabetes and hypothyroidism in pregnancy are the most common endocrine disorders which are considered as insulin resistant conditions. Maternal thyroid hormones play an important role in embryogenesis, fetal maturity, and child.s IQ level. It seems that SUBCLINICAL HYPOTHYROIDISM in women with gestational diabetes has a higher prevalence. Since thyroid function tests during pregnancy are not considered as part of a routine testing, therefore, we aimed to study thyroid function associated with INSULIN RESISTANCE in pregnant women.Materials and Methods: In this descriptive-analytic study, 142 pregnant women were randomly entered in GDM and normal groups. After obtaining demographic data and measuring all patients. BMI, Glucose Tolerance Test (GTT) was performed. Serum insulin, thyroid function test and anti.TPO antibody were measured on fasting blood samples. Data were analyzed using descriptive statistics, T-test, Chi-square test and multivariate regression analysis.Results: 68 pregnant women with GDM and 74 normal pregnant women participated in this study. Patients with GDM had higher age and BMI (P<0.0001). After eliminating the confounding variables, no significant correlation was found between TSH and insulin or HOMA-IR. Elevated ANTI-TPO was seen in 14.7% of GDM and 6.8% of normal women (P=0.171). Significant correlation of anti TPO level was found between both insulin level (P=0.01) and HOMA-IR (P=0.03).Conclusion: This study did not show any association between thyroid dysfunction and GDM. However, a higher ANTI-TPO level was seen in GDM patients. Further investigations with more sample sizes are recommended.

Cites

No record.

References

No record.

Cite

APA: Copy

SHARIFI, F., NEZAMDIBA, M., & KAMALI, K.. (2014). THYROID FUNCTION AND ITS RELATION TO INSULIN RESISTANCE IN WOMEN WITH GESTATIONAL DIABETES MELLITUS (GDM) COMPARED WITH HEALTHY PREGNANTWOMEN. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, 22(94), 61-71. SID. https://sid.ir/paper/61658/en

Vancouver: Copy

SHARIFI F., NEZAMDIBA M., KAMALI K.. THYROID FUNCTION AND ITS RELATION TO INSULIN RESISTANCE IN WOMEN WITH GESTATIONAL DIABETES MELLITUS (GDM) COMPARED WITH HEALTHY PREGNANTWOMEN. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH[Internet]. 2014;22(94):61-71. Available from: https://sid.ir/paper/61658/en

IEEE: Copy

F. SHARIFI, M. NEZAMDIBA, and K. KAMALI, “THYROID FUNCTION AND ITS RELATION TO INSULIN RESISTANCE IN WOMEN WITH GESTATIONAL DIABETES MELLITUS (GDM) COMPARED WITH HEALTHY PREGNANTWOMEN,” JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, vol. 22, no. 94, pp. 61–71, 2014, [Online]. Available: https://sid.ir/paper/61658/en

Related Journal Papers