Comparison of Anti Thyroid Peroxidase Antibody (TPOAb) levels in people with depression and healthy people: case control-study

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HOSSEINI MAHBOOBEHSADAT; RADFAR SHOKOFEH; Ghobadipour Hamid; RAMEZANI MAJID

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Journal: JOURNAL OF MILITARY MEDICINE Year:2019 | Volume:21 | Issue:3 Page(s): 243-250

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Title

Comparison of Anti Thyroid Peroxidase Antibody (TPOAb) levels in people with depression and healthy people: case control-study

Author(s)

HOSSEINI MAHBOOBEHSADAT | RADFAR SHOKOFEH | Ghobadipour Hamid | RAMEZANI MAJID | Issue Writer Certificate

Keywords

Antithyroid PeroxidaseQ2

DepressionQ1

ThyroxinQ1

Abstract

Background and Aim: Depression is a common psychiatric disorder with a high prevalence in military personnel. Recently, the relationship between Depression and some hormones has been reported. In current study, the serum levels of anti-thyroid peroxidase (anti-TPO), triiodothyronine (T3), Thyroxin (T4) and thyroidstimulating hormone (TSH) was assessed in people with Depression and compared with healthy control adults. Methods: In this case– control study, 45 people with Depression who were diagnosed using the Beck Depression test and DSM5, were referred to a military hospital. A total of 45 healthy participants who were matched according gender and age with the Depression group, were also enrolled. Levels of anti-TPO, T4, T3 and TSH were measured and compared in the two groups. Results: The mean ± standard deviation age was 36. 55± 11. 42 years in the case group and 35. 92± 11. 58 years in the matched control group. There was no significant difference in the mean serum level of Antithyroid Peroxidase, T3, T4 and TSH between the groups (P≥ 0. 05). There was no linear correlation between Antithyroid Peroxidase levels and Depression severity. Conclusion: As there was not difference regarding anti-TPO antibody levels between the depressed and healthy groups, it appears that anti-TPO antibody may not have a role in Depression.

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APA: Copy

HOSSEINI, MAHBOOBEHSADAT, RADFAR, SHOKOFEH, Ghobadipour, Hamid, & RAMEZANI, MAJID. (2019). Comparison of Anti Thyroid Peroxidase Antibody (TPOAb) levels in people with depression and healthy people: case control-study. JOURNAL OF MILITARY MEDICINE, 21(3 ), 243-250. SID. https://sid.ir/paper/62001/en

Vancouver: Copy

HOSSEINI MAHBOOBEHSADAT, RADFAR SHOKOFEH, Ghobadipour Hamid, RAMEZANI MAJID. Comparison of Anti Thyroid Peroxidase Antibody (TPOAb) levels in people with depression and healthy people: case control-study. JOURNAL OF MILITARY MEDICINE[Internet]. 2019;21(3 ):243-250. Available from: https://sid.ir/paper/62001/en

IEEE: Copy

MAHBOOBEHSADAT HOSSEINI, SHOKOFEH RADFAR, Hamid Ghobadipour, and MAJID RAMEZANI, “Comparison of Anti Thyroid Peroxidase Antibody (TPOAb) levels in people with depression and healthy people: case control-study,” JOURNAL OF MILITARY MEDICINE, vol. 21, no. 3 , pp. 243–250, 2019, [Online]. Available: https://sid.ir/paper/62001/en

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