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Information Journal Paper

Title

GC-MS ANALYSIS, FREE-RADICAL-SCAVENGING AND INSECTICIDAL ACTIVITIES OF ESSENTIAL OIL OF SCROPHULARIA OXYSEPALA BOISS

Pages

  1-5

Abstract

 Background: SCROPHULARIA OXYSEPALA Boiss. is endemic to western and central regions of Iran, and belongs to the genus Scrophularia (family: SCROPHULARIACEAE), which has long been used in traditional medicines. In the present work, chemical composition of the ESSENTIAL OIL of the aerial parts of this species was analyzed.Methods: The air-dried ground aerial parts of S. oxysepala were subjected to hydro-distillation. The resulting oil was analyzed, for the first time, by the gas chromatography/mass spectrometry (GC-MS) and gas chromatography/flame ionization detection (GC-FID). FREE-RADICAL-SCAVENGING activity of the ESSENTIAL OIL was determined by the DPPH assay. Adults of Oryzeaphilus mercator were used for contact toxicity INSECTICIDAL assay.Results: A total yield of 0.1 ml of ESSENTIAL OIL per 100 g of plant dry mass was obtained, and 15 compounds were identified, representing 91.2% of total oil. The ESSENTIAL OIL was characterized by a high content of aromatic compounds and PHYTOL. The main constituents were PHYTOL (25.3%), methyl benzyl alcohol (9.3%), dehydrodieugenol (6.7%), methyl benzaldehyde (5.3%) and EUGENOL (1.3%). The low level of FREE-RADICAL-SCAVENGING activity of the ESSENTIAL OIL was demonstrated by the RC50 value of 1.852mg/ml, and the INSECTICIDAL activity was also found to be low.Conclusion: The INSECTICIDAL activity of this ESSENTIAL OIL was not remarkable, but was time and concentration-dependent. The low FREE-RADICAL-SCAVENGING activity was probably due to its low percentage of phenolic compounds.

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    • Cite

    APA: Copy

    PASDARAN, ARDALAN, NAHAR, LUTFUN, ASNAASHARI, SOLMAZ, SARKER, SATYAJIT D., & DELAZAR, ABBAS. (2013). GC-MS ANALYSIS, FREE-RADICAL-SCAVENGING AND INSECTICIDAL ACTIVITIES OF ESSENTIAL OIL OF SCROPHULARIA OXYSEPALA BOISS. PHARMACEUTICAL SCIENCES, 19(1), 1-5. SID. https://sid.ir/paper/620632/en

    Vancouver: Copy

    PASDARAN ARDALAN, NAHAR LUTFUN, ASNAASHARI SOLMAZ, SARKER SATYAJIT D., DELAZAR ABBAS. GC-MS ANALYSIS, FREE-RADICAL-SCAVENGING AND INSECTICIDAL ACTIVITIES OF ESSENTIAL OIL OF SCROPHULARIA OXYSEPALA BOISS. PHARMACEUTICAL SCIENCES[Internet]. 2013;19(1):1-5. Available from: https://sid.ir/paper/620632/en

    IEEE: Copy

    ARDALAN PASDARAN, LUTFUN NAHAR, SOLMAZ ASNAASHARI, SATYAJIT D. SARKER, and ABBAS DELAZAR, “GC-MS ANALYSIS, FREE-RADICAL-SCAVENGING AND INSECTICIDAL ACTIVITIES OF ESSENTIAL OIL OF SCROPHULARIA OXYSEPALA BOISS,” PHARMACEUTICAL SCIENCES, vol. 19, no. 1, pp. 1–5, 2013, [Online]. Available: https://sid.ir/paper/620632/en

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