مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

PATHOGENESIS OF EPILEPSY: CHALLENGES IN ANIMAL MODELS

Pages

  1119-1132

Abstract

 Epilepsy is one of the most common chronic disorders affecting individuals of all ages. A greater understanding of pathogenesis in epilepsy will likely provide the basis fundamental for development of new antiepileptic therapies that aim to prevent the EPILEPTOGENESIS process or modify the progression of epilepsy in addition to treatment of epilepsy symptomatically. Therefore, several investigations have embarked on advancing knowledge of the mechanism underlying EPILEPTOGENESIS, understanding in mechanism of pharmacoresistance and discovering antiepileptogenic or disease-modifying therapy. ANIMAL MODELS play a crucial and significant role in providing additional insight into mechanism of EPILEPTOGENESIS. With the help of these models, EPILEPTOGENESIS process has been demonstrated to be involved in various molecular and biological pathways or processes. Hence, this article will discuss the known and postulated mechanisms of EPILEPTOGENESIS and challenges in using the ANIMAL MODELS.

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  • Cite

    APA: Copy

    YIN, YOW HUI, AHMAD, NURULUMI, & MAKMOR BAKRY, MOHD. (2013). PATHOGENESIS OF EPILEPSY: CHALLENGES IN ANIMAL MODELS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 16(11), 1119-1132. SID. https://sid.ir/paper/629230/en

    Vancouver: Copy

    YIN YOW HUI, AHMAD NURULUMI, MAKMOR BAKRY MOHD. PATHOGENESIS OF EPILEPSY: CHALLENGES IN ANIMAL MODELS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2013;16(11):1119-1132. Available from: https://sid.ir/paper/629230/en

    IEEE: Copy

    YOW HUI YIN, NURULUMI AHMAD, and MOHD MAKMOR BAKRY, “PATHOGENESIS OF EPILEPSY: CHALLENGES IN ANIMAL MODELS,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 16, no. 11, pp. 1119–1132, 2013, [Online]. Available: https://sid.ir/paper/629230/en

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