P63 IS MORE SENSITIVE AND SPECIFIC THAN 34βE12 TO DIFFERENTIATE ADENOCARCINOMA OF PROSTATE FROM CANCER MIMICKERS

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KALANTARI MAHMOUD REZA; ANVARI KAZEM; JABBARI HASAN; VARSHOEE TABRIZI FATEMEH

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Journal: Iranian Journal of Basic Medical Sciences Year:2014 | Volume:17 | Issue:7 Page(s): 497-501

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Title

P63 IS MORE SENSITIVE AND SPECIFIC THAN 34βE12 TO DIFFERENTIATE ADENOCARCINOMA OF PROSTATE FROM CANCER MIMICKERS

Author(s)

KALANTARI MAHMOUD REZA | ANVARI KAZEM | JABBARI HASAN | VARSHOEE TABRIZI FATEMEH | Issue Writer Certificate

Keywords

BASAL CELL MARKERS

CANCER MIMICKERS

PROSTATE ADENOCARCINOMA

Abstract

Objective (s): Prostate cancer is the world’s leading cause of cancer and the second cause of cancer-related death in men after lung cancer. Differentiation of PROSTATE ADENOCARCINOMA from benign prostate lesions and hyperplasia sometimes cannot be done on the basis of morphologic findings. Considering the fact that in the PROSTATE ADENOCARCINOMA there is no basal cell layer, BASAL CELL MARKERS can help to differentiate PROSTATE ADENOCARCINOMA from CANCER MIMICKERS.Materials and Methods: We studied 98 prostate biopsy blocks (40 adenocarcinoma and 58 benign lesions) for basal cell marker expression.Results: p63 and 34bE12 were negative in all PROSTATE ADENOCARCINOMA specimens, but all benign prostate hyperplasia and high grade intraepithelial neoplasia cases expressed them.Conclusion: BASAL CELL MARKERS can help to distinguish PROSTATE ADENOCARCINOMA from CANCER MIMICKERS.

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APA: Copy

KALANTARI, MAHMOUD REZA, ANVARI, KAZEM, JABBARI, HASAN, & VARSHOEE TABRIZI, FATEMEH. (2014). P63 IS MORE SENSITIVE AND SPECIFIC THAN 34βE12 TO DIFFERENTIATE ADENOCARCINOMA OF PROSTATE FROM CANCER MIMICKERS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 17(7), 497-501. SID. https://sid.ir/paper/630549/en

Vancouver: Copy

KALANTARI MAHMOUD REZA, ANVARI KAZEM, JABBARI HASAN, VARSHOEE TABRIZI FATEMEH. P63 IS MORE SENSITIVE AND SPECIFIC THAN 34βE12 TO DIFFERENTIATE ADENOCARCINOMA OF PROSTATE FROM CANCER MIMICKERS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2014;17(7):497-501. Available from: https://sid.ir/paper/630549/en

IEEE: Copy

MAHMOUD REZA KALANTARI, KAZEM ANVARI, HASAN JABBARI, and FATEMEH VARSHOEE TABRIZI, “P63 IS MORE SENSITIVE AND SPECIFIC THAN 34βE12 TO DIFFERENTIATE ADENOCARCINOMA OF PROSTATE FROM CANCER MIMICKERS,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 17, no. 7, pp. 497–501, 2014, [Online]. Available: https://sid.ir/paper/630549/en

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