A COMPARISON OF SERUM SELENIUM, ZINC AND COPPER LEVEL IN VISCERAL AND CUTANEOUS LEISHMANIASIS

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FARZIN LEILA; MOASSESI MOHAMMAD ESMAIL

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2014 | Volume:19 | Issue:4 Page(s): 355-357

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Title

A COMPARISON OF SERUM SELENIUM, ZINC AND COPPER LEVEL IN VISCERAL AND CUTANEOUS LEISHMANIASIS

Author(s)

FARZIN LEILA | MOASSESI MOHAMMAD ESMAIL | Issue Writer Certificate

Keywords

ANTIOXIDANT TRACE ELEMENTS

ATOMIC ABSORPTION SPECTROSCOPY

CUTANEOUS LEISHMANIASIS

TRACE ELEMENTS

VISCERAL AND CUTANEOUS LEISHMANIASIS

Abstract

Background: Leishmaniasis is a widespread tropical infection, which has a high incidence rate in Iran. Visceral leishmaniasis (VL) and CUTANEOUS LEISHMANIASIS (CL) are two forms of this disease. In this study, we investigated if selenium (Se), zinc (Zn) and copper (Cu) levels differ in different forms of leishmaniasis. Materials and Methods: To determine if leishmaniasis has effects on TRACE ELEMENTS status, they were determined by atomic absorption spectrometry (AAS) in patients (n=155, 95 CL and 60 VL) and control group (n=100).Results: Our findings indicate that there is a significant difference in the values of Se and Zn between control and patient groups (P<0.0001 and P<0.001, respectively). Se and Zn levels were 3.65±0.88 and 67.24±18.76 mg/dL in the leishmaniasis patients, and these values were observed to be statistically lower compared to the control groups (11.10±2.37 and 119.61±26.18 mg/dL, respectively). Meanwhile, no significant difference in status of Cu was found between the cases (110.55±29.25 mg/dL) and healthy subjects (91.42±27.54 mg/dL) (P>0.05). When the patients were divided into two groups, there appeared to be a significant decrease (P<0.001) in Se concentration for VL patients (2.57±0.64 mg/dL) compared with CL patients (4.33±1.06 mg/dL).Conclusion: Based on these results, serum Se and Zn levels could be a useful marker for the pathophysiology of leishmaniasis.

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APA: Copy

FARZIN, LEILA, & MOASSESI, MOHAMMAD ESMAIL. (2014). A COMPARISON OF SERUM SELENIUM, ZINC AND COPPER LEVEL IN VISCERAL AND CUTANEOUS LEISHMANIASIS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 19(4), 355-357. SID. https://sid.ir/paper/631079/en

Vancouver: Copy

FARZIN LEILA, MOASSESI MOHAMMAD ESMAIL. A COMPARISON OF SERUM SELENIUM, ZINC AND COPPER LEVEL IN VISCERAL AND CUTANEOUS LEISHMANIASIS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2014;19(4):355-357. Available from: https://sid.ir/paper/631079/en

IEEE: Copy

LEILA FARZIN, and MOHAMMAD ESMAIL MOASSESI, “A COMPARISON OF SERUM SELENIUM, ZINC AND COPPER LEVEL IN VISCERAL AND CUTANEOUS LEISHMANIASIS,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 19, no. 4, pp. 355–357, 2014, [Online]. Available: https://sid.ir/paper/631079/en

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